Evidence map›Paper›PMID 29135988›Full record

ArticlePloS one2017

Evolution of acute hepatitis C virus infection in a large European city: Trends and new patterns.

César Garriga, Sandra Manzanares-Laya, Patricia García de Olalla, Pilar Gorrindo, Sabela Lens, Ricard Solà, María Martínez-Rebollar, Montserrat Laguno, Jordi Navarro, Xavier Torras and 8 more

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. SARS-CoV-2 vs. Hepatitis Virus Infection Risk in the Hemodialysis Population: What Should We Expect?International journal of environmental research and public health · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

César GarrigaEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0001-7073-3611
Sandra Manzanares-LayaEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Patricia García de OlallaEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Pilar GorrindoEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Sabela LensLiver Unit, Hospital Clínic, Barcelona. IDIBAPS, Barcelona, Spain.
Ricard SolàInternal Medicine-Infectious Diseases, Hospital del Mar, Barcelona, Spain.
María Martínez-RebollarHospital Clinic- August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain.
Montserrat LagunoHospital Clinic- August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain.
Jordi NavarroInfectious Diseases, Hospital Vall de Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
Xavier TorrasDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, CIBERehd, Barcelona, Spain.
Mercè GurguíInfectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
María-Jesús BarberáSexually Transmitted Infections Unit, Hospital Vall de Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
Josep QuerLiver Unit, Internal Medicine, Laboratory of Malalties Hepàtiques, Vall d'Hebron Institut de Recerca-Hospital Universitari Vall d´Hebron, (VHIR-HUVH), Universitat Autònoma de Barcelona, Barcelona, Spain.
Eva MasdeuEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Pere SimónEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Miriam RosEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Anna de AndrésEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.
Joan A CaylàEpidemiology Service, Public Health Agency of Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aims of this study were to describe the evolution of acute hepatitis C virus (HCV) infections since 2004 and to determine its associated factors. Acute HCV infections diagnosed in Barcelona from 2004 to 2015 were included. Incidence ratios (IR) were then estimated for sex and age groups. Cases were grouped between 2004-2005, 2006-2011 and 2012-2015, and their incidence rate ratios (IRR) were calculated. In addition, risk factors for acute HCV infection were identified using multinomial logistic regression for complete, available and multiple imputed data. 204 new HCV cases were identified. Two peaks of higher IR of acute HCV infection in 2005 and 2013 were observed. Men and those aged 35-54 had higher IR. IRR for men was 2.9 times greater than in women (95% confidence intervals (CI): 1.8 ‒ 4.7). Factors related to the period 2012-2015 (versus 2006-2011) were: a) sexual risk factor for transmission versus nosocomial (relative-risk ratio (RRR): 13.0; 95% CI: 2.3 ‒ 72.1), b) higher educated versus lower (RRR: 5.4; 95% CI: 1.6 ‒ 18.7), and c) HIV co-infected versus not HIV-infected (RRR: 53.1; 95% CI: 5.7 ‒ 492.6). This is one of the few studies showing IR and RRRs of acute HCV infections and the first focused on a large city in Spain. Sexual risk for transmission between men, higher educational level and HIV co-infection are important factors for understanding current HCV epidemic. There has been a partial shift in the pattern of the risk factor for transmission from nosocomial to sexual.

Indexed as

AdultEuropeFemaleHepatitis CHumansMaleMiddle AgedRisk FactorsSpain

Identifiers

PMID29135988
PMCPMC5685589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.