ReviewMolecules (Basel, Switzerland)2017
The killer of Socrates: Coniine and Related Alkaloids in the Plant Kingdom.
Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 84 citations in OpenAlex.
- Liquid Chromatography-Mass Spectrometry-Based Molecular Profiling of Vertigoheel.International journal of molecular sciences · 2026Article
- A 20-Year Retrospective Analysis of Plant Poisoning Cases at the Naval Hospital, Varna, Bulgaria.Toxins · 2025Article
- Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature's secrets in forensic science.Natural products and bioprospecting · 2025Review
- Recent highlights in the synthesis and biological significance of pyrazole derivatives.Heliyon · 2024Review
- Mass Spectrometry Imaging of Coniine and Other Hemlock Alkaloids after On-Tissue Derivatization Reveals Distinct Alkaloid Distributions in the Plant.Journal of natural products · 2024Article
- Toxic Plants and Their Impact on Livestock Health and Economic Losses: A Comprehensive Review.Journal of toxicology · 2024Review
- The Wild Carrot (Plants (Basel, Switzerland) · 2023Review
- Ligand-modulated nickel-catalyzed regioselective silylalkylation of alkenes.Nature communications · 2023Article
- Synergistic Responses of Tibetan Sheep Rumen Microbiota, Metabolites, and the Host to the Plateau Environment.International journal of molecular sciences · 2023Article
- Teodorico Borgognoni's Formulary for Thirteenth Century Anesthetic Preparations.Life (Basel, Switzerland) · 2023Article
- Article
- Electrochemically Enabled Total Syntheses of Natural Products.ChemElectroChem · 2023Article
- Antibiofilm properties of bioactive compounds from Actinomycetes against foodborne and fish pathogens.Scientific reports · 2022Article
- De novo transcriptome assembly of Conium maculatum L. to identify candidate genes for coniine biosynthesis.Scientific reports · 2022Article
- A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides.PNAS nexus · 2022Article
- Secondary Metabolites with Biomedical Applications from Plants of the Sarraceniaceae Family.International journal of molecular sciences · 2022Review
- Phytochemical profiling of antimicrobial and potential antioxidant plant:Frontiers in plant science · 2022Article
- Alkyl Group Migration in Ni-Catalyzed Conjunctive Coupling with C(spOrganic letters · 2020Article
- Turning Meadow Weeds Into Valuable Species for the Romanian Ethnomedicine While Complying With the Environmentally Friendly Farming Requirements of the European Union's Common Agricultural Policy.Frontiers in pharmacology · 2020Review
- Comparison of Strategies to Overcome Drug Resistance: Learning from Various Kingdoms.Molecules (Basel, Switzerland) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coniine, a polyketide-derived alkaloid, is poisonous to humans and animals. It is a nicotinic acetylcholine receptor antagonist, which leads to inhibition of the nervous system, eventually causing death by suffocation in mammals. Coniine's most famous victim is Socrates who was sentenced to death by poison chalice containing poison hemlock in 399 BC. In chemistry, coniine holds two historical records: It is the first alkaloid the chemical structure of which was established (in 1881), and that was chemically synthesized (in 1886). In plants, coniine and twelve closely related alkaloids are known from poison hemlock (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.