Evidence map›Paper›PMID 29135917›Full record

ArticleMarine drugs2017

Asperlin Inhibits LPS-Evoked Foam Cell Formation and Prevents Atherosclerosis in ApoE

Yue Zhou, Ran Chen, Dong Liu, Chongming Wu, Peng Guo, Wenhan Lin

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Genes & diseases · 2023
    Article
  10. MicroRNA-320b Modulates Cholesterol Efflux and Atherosclerosis.Journal of atherosclerosis and thrombosis · 2022
    Article
  11. Article
  12. Article
  13. Marine Natural Products and Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021
    Review
  14. Article
  15. Article
  16. Biocontrol Potential ofFrontiers in microbiology · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yue ZhouPharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China. xiaoyuzhou5213@sina.com.
Ran ChenPharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China. cran_lxj@sina.com.
Dong LiuState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China. liudong_1982@126.com.
Chongming WuPharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China. cmwu@implad.ac.cn.
Peng GuoPharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China. pguo@imaplad.ac.cn.
Wenhan LinState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China. whlin@bjmu.edu.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asperlin is a marine-derived natural product with antifungal and anti-inflammatory activities in vitro. In the present study, we isolated asperlin from a marine

Indexed as

AnimalsAortaApolipoproteins EAtherosclerosisCell LineDiet, High-FatEpoxy CompoundsFoam CellsInflammationInterleukin-1betaLipopolysaccharidesLipoproteins, LDLMacrophagesMaleMiceMice, Inbred C57BLApolipoproteins EasperlinEpoxy CompoundsInterleukin-1betaLipopolysaccharidesLipoproteins, LDLNitric Oxide Synthase Type IIoxidized low density lipoproteinPyronesTumor Necrosis Factor-alphaasperlinatherosclerosisfoam cellinflammationM1/M2 polarizationmacrophage

Identifiers

PMID29135917
PMCPMC5706047
OpenAlexW2770742083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.