Evidence map›Paper›PMID 29135777›Full record

ArticleMedical care2017

Validity of Using Inpatient and Outpatient Administrative Codes to Identify Acute Venous Thromboembolism: The CVRN VTE Study.

Margaret C Fang, Dongjie Fan, Sue Hee Sung, Daniel M Witt, John R Schmelzer, Steven R Steinhubl, Steven H Yale, Alan S Go

Abstract read
In one paragraph

Article in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 1 synthesis or guideline pooled it.

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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Margaret C Fang*Division of Hospital Medicine, University of California, San Francisco †Division of Research, Kaiser Permanente Northern California, Oakland, CA ‡Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, UT §Office for Health Services, Marshfield Clinic Research Foundation, Marshfield, WI ∥Geisinger Health System, Center for Health Research, Danville, PA ¶Scripps Translational Science Institute, La Jolla, CA #Departments of Epidemiology, Biostatistics and Medicine, University of California, San Francisco **Department of Health Research and Policy, Stanford University School of Medicine, Palo Alto, CA.
Dongjie Fan
Sue Hee Sung
Daniel M Witt
John R Schmelzer
Steven R Steinhubl
Steven H Yale
Alan S Go

Funding

Anticoagulation Treatment and Long-Term Outcomes After Venous ThromboembolismR01HL103820 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FANG, MARGARET C. · 2010 to 2014
$3.6M
NHLBI NIH HHS R01 HL103820
6 · The paper itself

Abstract

backgroundAdministrative data are frequently used to identify venous thromboembolism (VTE) for research and quality reporting. However, the validity of these codes, particularly in outpatients, has not been well-established.

objectiveTo determine how well International Classification of Diseases, Ninth Revision (ICD-9) codes for VTE predict chart-confirmed acute VTE in inpatient and outpatients. PATIENTS AND

methodsWe selected 4642 adults with an incident ICD-9 diagnosis of VTE between years 2004 and 2010 from the Cardiovascular Research Network Venous Thromboembolism cohort study. Medical charts were reviewed to determine validity of events. Positive predictive values (PPVs) of ICD-9 codes were calculated as the number of chart-validated VTE events divided by the number with specific VTE codes. Analyses were stratified by VTE type [pulmonary embolism (PE), deep venous thrombosis (DVT)], code position (primary, secondary), and setting [hospital/emergency department (ED), outpatient].

resultsThe PPV for any diagnosis of VTE was 64.6% for hospital/ED patients and 30.9% for outpatients. Primary diagnosis codes from hospital/ED patients were more likely to represent acute VTE than secondary diagnosis codes (78.9% vs. 44.4%, P<0.001). Primary hospital/ED codes for PE and lower extremity DVT had higher PPV than for upper extremity DVT (89.1%, 74.9%, and 58.1%, respectively). Outpatient codes were poorly predictive of acute VTE: 28.0% for PE and 53.6% for lower extremity DVT.

conclusionsICD-9 codes for VTE obtained from outpatient encounters or from secondary diagnosis codes do not reliably reflect acute VTE. More accurate ways of identifying VTE in outpatients are needed before these codes can be adopted for research or policy purposes.

Indexed as

InpatientsOutpatientsQuality Indicators, Health CareAdultCohort StudiesFemaleHumansMaleMiddle AgedValidation Studies as TopicVenous ThromboembolismVenous Thrombosis

Identifiers

PMID29135777
PMCPMC5125903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.