Evidence map›Paper›PMID 29135654›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Cost-Effectiveness of Peer- Versus Venue-Based Approaches for Detecting Undiagnosed HIV Among Heterosexuals in High-Risk New York City Neighborhoods.

Elizabeth R Stevens, Kimberly A Nucifora, Qinlian Zhou, Ronald Scott Braithwaite, Charles M Cleland, Amanda S Ritchie, Alexandra H Kutnick, Marya V Gwadz

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elizabeth R StevensDepartment of Population Health, NYU School of Medicine, New York, NY.
Kimberly A NuciforaDepartment of Population Health, NYU School of Medicine, New York, NY.
Qinlian ZhouDepartment of Population Health, NYU School of Medicine, New York, NY.
Ronald Scott BraithwaiteDepartment of Population Health, NYU School of Medicine, New York, NY.
Charles M ClelandCenter for Drug Use and HIV Research, Rory Meyers College of Nursing, New York University, New York, NY.
Amanda S RitchieCenter for Drug Use and HIV Research, Rory Meyers College of Nursing, New York University, New York, NY.
Alexandra H KutnickCenter for Drug Use and HIV Research, Rory Meyers College of Nursing, New York University, New York, NY.
Marya V GwadzCenter for Drug Use and HIV Research, Rory Meyers College of Nursing, New York University, New York, NY.

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
BEHAVIORAL SCI TRAINING IN DRUG ABUSE RESEARCHT32DA007233 · NIDA · PUBLIC HEALTH SOLUTIONS · PI GOLDSAMT, LLOYD A · 1985 to 2023
$20.2M
Peer-driven Intervention to Seek, Test & Treat Heterosexuals at High Risk for HIVR01DA032083 · NIDA · NEW YORK UNIVERSITY · PI GWADZ, MARYA · 2011 to 2015
$7.5M
NIDA NIH HHS P30 DA011041NIDA NIH HHS R01 DA032083NIDA NIH HHS T32 DA007233
6 · The paper itself

Abstract

introductionWe used a computer simulation of HIV progression and transmission to evaluate the cost-effectiveness of a scale-up of 3 strategies to seek out and test individuals with undiagnosed HIV in New York City (NYC).

settingHypothetical NYC population.

methodsWe incorporated the observed effects and costs of the 3 "seek and test" strategies in a computer simulation of HIV in NYC, comparing a scenario in which the strategies were scaled up with a 1-year implementation or a long-term implementation with a counterfactual scenario with no scale-up. The simulation combined a deterministic compartmental model of HIV transmission with a stochastic microsimulation of HIV progression, calibrated to NYC epidemiological data from 2003 to 2015. The 3 approaches were respondent-driven sampling (RDS) with anonymous HIV testing ("RDS-A"), RDS with a 2-session confidential HIV testing approach ("RDS-C"), and venue-based sampling ("VBS").

resultsRDS-A was the most cost-effective strategy tested. When implemented for only 1 year and then stopped thereafter, using a societal perspective, the cost per quality-adjusted life-year (QALY) gained versus no intervention was $812/QALY, $18,110/QALY, and $20,362/QALY for RDS-A, RDS-C, and VBS, respectively. When interventions were implemented long term, the cost per QALY gained versus no intervention was cost-saving, $31,773/QALY, and $35,148/QALY for RDS-A, RDS-C, and VBS, respectively. When compared with RDS-A, the incremental cost-effectiveness ratios for both VBS and RDS-C were dominated.

conclusionsThe expansion of the RDS-A strategy would substantially reduce HIV-related deaths and new HIV infections in NYC, and would be either cost-saving or have favorable cost-effectiveness.

Indexed as

Cost-Benefit AnalysisHeterosexualityComputer SimulationDiagnostic Tests, RoutineDisease Transmission, InfectiousFemaleHIV InfectionsHumansMaleMass ScreeningNew York CityQuality-Adjusted Life YearsUrban Population

Identifiers

PMID29135654
PMCPMC5762425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.