Evidence map›Paper›PMID 29135650›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Pathways From HIV-Related Stigma to Antiretroviral Therapy Measures in the HIV Care Cascade for Women Living With HIV in Canada.

Carmen H Logie, Ashley Lacombe-Duncan, Ying Wang, Angela Kaida, Tracey Conway, Kath Webster, Alexandra de Pokomandy, Mona R Loutfy, Aranka Anema, Denise Becker and 112 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Effective Messages to Reduce Stigma among People Newly Diagnosed with HIV during Rapid ART Initiation.International journal of environmental research and public health · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Beyond HIV: An urgent need for a syndemic and gender-based approach in the Prairie provinces in Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

122 authors.

Carmen H LogieFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Ashley Lacombe-DuncanFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Ying WangFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Angela KaidaFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Tracey ConwayWomen's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
Kath WebsterFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Alexandra de PokomandyDepartment of Family Medicine, McGill University, Montreal, Quebec, Canada.
Mona R LoutfyWomen's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
Aranka Anema
Denise Becker
Lori Brotto
Allison Carter
Claudette Cardinal
Guillaume Colley
Erin Ding
Janice Duddy
Nada Gataric
Robert S Hogg
Terry Hosward
Shahab Jabbari
Evin Jones
Mary Kestler
Andrea Langlois
Viviane Lima
Elisa Lloyd-Smith
Melissa Medjuck
Cari Miller
Deborah Money
Valerie Nicholson
Gina Ogilvie
Sophie Patterson
Neora Pick
Eric Roth
Kate Salters
Margarite Sanchez
Jacquie Sas
Paul Sereda
Marcie Summers
Christina Tom
Lu Wang
Kath Webster
Wendy Zhang
Rahma Abdul-Noor
Jonathan Angel
Fatimatou Barry
Greta Bauer
Kerrigan Beaver
Anita Benoit
Breklyn Bertozzi
Sheila Borton
Tammy Bourque
Jason Brophy
Ann Burchell
Allison Carlson
Lynne Cioppa
Jeffrey Cohen
Tracey Conway
Curtis Cooper
Jasmine Cotnam
Janette Cousineau
Annette Fraleigh
Brenda Gagnier
Claudine Gasingirwa
Saara Greene
Trevor Hart
Shazia Islam
Charu Kaushic
Logan Kennedy
Desiree Kerr
Maxime Kiboyogo
Gladys Kwaramba
Lynne Leonard
Johanna Lewis
Carmen Logie
Shari Margolese
Marvelous Muchenje
Mary Ndungʼu
Kelly OʼBrien
Charlene Ouellette
Jeff Powis
Corinna Quan
Janet Raboud
Anita Rachlis
Edward Ralph
Sean Rourke
Sergio Rueda
Roger Sandre
Fiona Smaill
Stephanie Smith
Tsitsi Tigere
Wangari Tharao
Sharon Walmsley
Wendy Wobeser
Jessica Yee
Mark Yudin
Jean-Guy Baril
Nora Butler Burke
Pierrette Clément
Janice Dayle
Danièle Dubuc
Mylène Fernet
Danielle Groleau
Aurélie Hot
Marina Klein
Carrie Martin
Lyne Massie
Brigitte Ménard
Nadia OʼBrien
Joanne Otis
Doris Peltier
Alie Pierre
Karène Proulx-Boucher
Danielle Rouleau
Édénia Savoie
Cécile Tremblay
Benoit Trottier
Sylvie Trottier
Christos Tsoukas
Jacqueline Gahagan
Catherine Hankins
Renee Masching
Susanna Ogunnaike-Cooke

Funding

CIHR CTN 262CIHR MOP-111041
6 · The paper itself

Abstract

backgroundAssociations between HIV-related stigma and reduced antiretroviral therapy (ART) adherence are widely established, yet the mechanisms accounting for this relationship are underexplored. There has been less attention to HIV-related stigma and its associations with ART initiation and current ART use. We examined pathways from HIV-related stigma to ART initiation, current ART use, and ART adherence among women living with HIV in Canada.

methodsWe used baseline survey data from a national cohort of women living with HIV in Canada (n = 1425). Structural equation modeling using weighted least squares estimation methods was conducted to test the direct effects of HIV-related stigma dimensions (personalized, negative self-image, and public attitudes) on ART initiation, current ART use, and 90% ART adherence, and indirect effects through depression and HIV disclosure concerns, adjusting for sociodemographic factors.

resultsIn the final model, the direct paths from personalized stigma to ART initiation (β = -0.104, P < 0.05) and current ART use (β = -0.142, P < 0.01), and negative self-image to ART initiation (β = -0.113, P < 0.01) were significant, accounting for the mediation effects of depression and HIV disclosure concerns. Depression mediated the pathways from personalized stigma to ART adherence, and negative self-image to current ART use and ART adherence. Final model fit indices suggest that the model fit the data well [χ(25) = 90.251, P < 0.001; comparative fit index = 0.945; root-mean-square error of approximation = 0.044].

conclusionsHIV-related stigma is associated with reduced likelihood of ART initiation and current ART use, and suboptimal ART adherence. To optimize the benefit of ART among women living with HIV, interventions should reduce HIV-related stigma and address depression.

Indexed as

Social StigmaAdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCanadaCross-Sectional StudiesFemaleHIV InfectionsHumansMedication AdherenceMiddle AgedAnti-Retroviral Agents

Identifiers

PMID29135650
PMCPMC5770113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.