Evidence map›Paper›PMID 29134564›Full record

GuidelineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2018

SEOM clinical guideline for treatment of kidney cancer (2017).

E Gallardo, M J Méndez-Vidal, J L Pérez-Gracia, J M Sepúlveda-Sánchez, M Campayo, I Chirivella-González, X García-Del-Muro, A González-Del-Alba, E Grande, C Suárez

Erratum issuedAbstract readPractice Guideline
In one paragraph

Guideline in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Assessing the methodological strengths and limitations of the Spanish Society of Medical Oncology (SEOM) guidelines: a critical appraisal using AGREE II and AGREE-REX tool.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  5. Article
  6. The Role of Long Noncoding RNA (lncRNAs) Biomarkers in Renal Cell Carcinoma.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Clinical translation of immunomodulatory therapeutics.Advanced drug delivery reviews · 2021
    Review
  9. Long-term outcomes of CT-guided percutaneous cryoablation of T1a and T1b renal cell carcinoma.Diagnostic and interventional radiology (Ankara, Turkey) · 2021
    Article
  10. Article
  11. Article
  12. New Treatments in Renal Cancer: The AhR Ligands.International journal of molecular sciences · 2020
    Review
  13. Article
  14. 2017 SEOM guidelines: a multidisciplinary approach.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

E GallardoMedical Oncology Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Parc Taulí, 1, 08208, Sabadell, Spain.
M J Méndez-VidalMedical Oncology Department, Maimonides Institute of Biomedical Research (IMIBIC), Reina Sofía Hospital, University of Córdoba, Córdoba, Spain.
J L Pérez-GraciaMedical Oncology Department, Clinica Universidad de Navarra, Pamplona, Spain.
J M Sepúlveda-SánchezMedical Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
M CampayoMedical Oncology Department, Hospital Universitari Mutua Terrassa, Terrassa, Spain.
I Chirivella-GonzálezMedical Oncology Department, Hospital Clínico, Universidad de Valencia, Valencia, Spain.
X García-Del-MuroMedical Oncology Department, Institut Catala d'Oncologia, Idibell, Universitat de Barcelona, Barcelona, L'Hospitalet de Llobregat, Spain.
A González-Del-AlbaOncology Department, Hospital Universitario Son Espases, Palma De Mallorca, Spain.
E GrandeMedical Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
C SuárezMedical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona, Barcelona, Spain. csuarez@vhio.net.ORCID http://orcid.org/0000-0002-0502-5528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this article is to provide recommendations about the management of kidney cancer. Based on pathologic and molecular features, several kidney cancer variants were described. Nephron-sparing techniques are the gold standard of localized disease. After a randomized trial, sunitinib could be considered in adjuvant treatment in high-risk patients. Patients with advanced disease constitute a heterogeneous population. Prognostic classification should be considered. Both sunitinib and pazopanib are the standard options for first-line systemic therapy in advanced renal cell carcinoma. Based on the results of two randomized trials, both nivolumab and cabozantinib should be considered the standard for second and further lines of therapy. Response evaluation for present therapies is a challenge.

Indexed as

Carcinoma, Renal CellHumansKidney NeoplasmsKidney cancerMolecular pathologySystemic therapy

Identifiers

PMID29134564
PMCPMC5785618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.