Evidence map›Paper›PMID 29134404›Full record

ArticleLasers in medical science2018

Curcumin-mediated anti-microbial photodynamic therapy against Candida dubliniensis biofilms.

Paula Volpato Sanitá, Ana Cláudia Pavarina, Lívia Nordi Dovigo, Ana Paula Dias Ribeiro, Mariana Carvalho Andrade, Ewerton Garcia de Oliveira Mima

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy onInternational journal of molecular sciences · 2024
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Photodynamic disinfection and its role in controlling infectious diseases.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Antimicrobial effect onLaser therapy · 2019
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paula Volpato SanitáDepartment of Dental Materials and Prosthodontics, School of Dentistry, Araraquara, São Paulo State University (UNESP), Rua Humaitá, n° 1680, Araraquara, SP, 14801-903, Brazil.
Ana Cláudia PavarinaDepartment of Dental Materials and Prosthodontics, School of Dentistry, Araraquara, São Paulo State University (UNESP), Rua Humaitá, n° 1680, Araraquara, SP, 14801-903, Brazil.
Lívia Nordi DovigoDepartment of Social Dentistry, School of Dentistry, Araraquara, São Paulo State University (UNESP), Rua Humaitá, 1680, Araraquara, SP, 14801-903, Brazil.
Ana Paula Dias RibeiroDepartment of Restorative Dental Sciences, College of Dentistry, University of Florida, Center Dr. 1395, Gainesville, FL, 32610, USA.
Mariana Carvalho AndradeDepartment of Dental Materials and Prosthodontics, School of Dentistry, Araraquara, São Paulo State University (UNESP), Rua Humaitá, n° 1680, Araraquara, SP, 14801-903, Brazil.
Ewerton Garcia de Oliveira MimaDepartment of Dental Materials and Prosthodontics, School of Dentistry, Araraquara, São Paulo State University (UNESP), Rua Humaitá, n° 1680, Araraquara, SP, 14801-903, Brazil. ewertonmima@foar.unesp.br.

Funding

CEPOF RIDC FAPESP 13/07276-1FAPESP 09/17975-9FAPESP 10/05425-1
6 · The paper itself

Abstract

The purpose of this study was to evaluate the effectiveness of anti-microbial photodynamic therapy (aPDT) mediated by curcumin (Cur) associated with LED light against biofilms of Candida dubliniensis, and further, investigate cellular uptake and drug penetration through the biofilms under confocal laser scanning microscopy (CLSM). Four C. dubliniensis strains were tested: three clinical isolates from HIV-positive patients and one reference strain (CBS 7987). Biofilms were treated with three Cur concentrations (20.0, 30.0, and 40.0 μM). All samples were incubated in the dark for 20 min and exposed to a 5.28 J/cm

Indexed as

PhotochemotherapyAnti-Infective AgentsBiofilmsCandidaColony Count, MicrobialCurcuminHumansMicroscopy, ConfocalPlanktonAnti-Infective AgentsCurcuminBiofilmCandida dubliniensisCurcuminLight-emitted diodePhotochemotherapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.