Evidence map›Paper›PMID 29134398›Full record

ArticleClinical & experimental metastasis2017

MicroRNAs and their role for T stage determination and lymph node metastasis in early colon carcinoma.

Melanie Rammer, Gerald Webersinke, Sophie Haitchi-Petnehazy, Eva Maier, Hubert Hackl, Pornpimol Charoentong, Theodora Malli, Maria Steinmair, Andreas L Petzer, Holger Rumpold

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical & experimental metastasis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. miR-152-3p Affects the Progression of Colon Cancer via the KLF4/IFITM3 Axis.Computational and mathematical methods in medicine · 2020
    Article
  7. Article
  8. Review
  9. Article
  10. cfRNAs as biomarkers in oncology - still experimental or applied tool for personalized medicine already?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
  11. Good or not good: Role of miR-18a in cancer biology.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Melanie RammerLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I: Medical Oncology, Hematology and Gastroenterology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.ORCID 0000-0002-2884-2731
Gerald WebersinkeLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I: Medical Oncology, Hematology and Gastroenterology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Sophie Haitchi-PetnehazyDepartment of Pathology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Eva MaierDepartment of Pathology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Hubert HacklDivision of Bioinformatics, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-4055-3841
Pornpimol CharoentongDivision of Bioinformatics, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-9028-725X
Theodora MalliLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I: Medical Oncology, Hematology and Gastroenterology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.ORCID 0000-0003-4244-7954
Maria SteinmairDepartment of Pathology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Andreas L PetzerDepartment of Internal Medicine I: Medical Oncology, Hematology and Gastroenterology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Holger RumpoldDepartment of Internal Medicine I: Medical Oncology, Hematology and Gastroenterology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria. holger.rumpold@vlkh.net.ORCID 0000-0002-4118-0111
Ordensklinikum Linz Barmherzige Schwestern · ATInnsbruck Medical University · ATLandeskrankenhaus Feldkirch · AT

Funding

Krebshilfe Oberösterreich research grant
6 · The paper itself

Abstract

Worldwide, colon cancer is among the most common cancer entities. Understanding the molecular background is the key to enable accurate stage determination, which is crucial to assess optimal therapy options. The search for preoperative biomarkers is ongoing. In recent years, several studies have proposed a diagnostic and prognostic role for miRNAs in cancer. Aim of this study was to evaluate miRNA expression patterns correlating with tumor stage, especially lymph node metastasis, in primary colon carcinoma tissue. Screening was accomplished using GeneChip

Indexed as

AdultAgedAged, 80 and overBiomarkers, TumorColonic NeoplasmsFemaleHumansLymphatic MetastasisMaleMicroRNAsMiddle AgedNeoplasm StagingYoung AdultBiomarkers, TumorMicroRNAsBiomarkersColonic neoplasmsLymphatic metastasisMicroRNAsRisk assessment

Identifiers

PMID29134398
OpenAlexW2771030635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.