Evidence map›Paper›PMID 29134274›Full record

ArticleInternational journal of colorectal disease2018

Harvest of lymph nodes in colorectal cancer depends on demographic and clinical characteristics of the patients.

Shu-Kay Ng, Cu-Tai Lu, Sahar Pakneshan, Melissa Leung, Simon Siu, Alfred King-Yin Lam

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Article in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shu-Kay NgSchool of Medicine, Griffith Medical School, Griffith University, Gold Coast, QLD, 4222, Australia.
Cu-Tai LuDepartment of Surgery, Gold Coast Hospital, Gold Coast, QLD, Australia.
Sahar PakneshanSchool of Medicine, Griffith Medical School, Griffith University, Gold Coast, QLD, 4222, Australia.
Melissa LeungSchool of Medicine, Griffith Medical School, Griffith University, Gold Coast, QLD, 4222, Australia.
Simon SiuSchool of Medicine, Griffith Medical School, Griffith University, Gold Coast, QLD, 4222, Australia.
Alfred King-Yin LamSchool of Medicine, Griffith Medical School, Griffith University, Gold Coast, QLD, 4222, Australia. a.lam@griffith.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to study the impact of clinical factors on the lymph node sampling in a large cohort of patients with colorectal cancer.

methodsA colorectal cancer database of 2298 patients in Queensland, Australia, was established. Zero-inflated regression method was used to model positive lymph node counts given the number of lymph nodes examined, with patient's demographic and clinical factors as covariates in the model. Sensitivity and survival analyses were performed to illustrate the applicability of the recommendation of the minimum number of lymph nodes need to be pathologically examined.

resultsYounger patients with a larger sized tumour located at the left colon or rectum require fewer lymph nodes to be pathologically examined. Overall, 45.9% of the patients require eight or nine lymph nodes and 31.5% needs ten or 11 lymph nodes to be harvested for pathological examination. A simple formula could be used to obtain the minimum number of lymph node sampling required in patients with colorectal cancer based on patients' age as well as site and dimension of the cancer.

conclusionsThe findings provide practical information about that the minimum number of lymph nodes that could be harvested at the time of collection of lymph nodes for pathological examination for patients with colorectal cancer. The minimum number of lymph nodes harvested depends on demographic (age) and clinical (location and dimension of cancer) characteristics of the patients with colorectal cancer.

Indexed as

DemographyAdolescentAdultAgedAged, 80 and overColorectal NeoplasmsFemaleHumansLymph NodesMaleMiddle AgedYoung AdultAdenocarcinomaColorectal cancerHarvestLymph nodePathology

Identifiers

PMID29134274

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.