Evidence map›Paper›PMID 29134184›Full record

ArticleOcular oncology and pathology2017

Extranodal Marginal Zone Lymphoma of Ocular Adnexa: Outcomes following Radiation Therapy.

Sean Platt, Yahya Al Zahrani, Nakul Singh, Brian Hill, Sheen Cherian, Arun D Singh

Open access · bronzeAbstract read
In one paragraph

Article in Ocular oncology and pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The outcome of radiation therapy as a primary treatment in orbital lymphoma: a systematic review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Survival in B-cell primary ocular lymphoma 1997-2014: a population-based study.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2018
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sean PlattDepartment of Ophthalmic Oncology, Cole Eye Institute, Cleveland, Ohio, USA.
Yahya Al ZahraniDepartment of Ophthalmic Oncology, Cole Eye Institute, Cleveland, Ohio, USA.
Nakul SinghCase Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Brian HillDepartment of Hematologic Oncology and Blood Disorders, Taussig Cancer Institute, Cleveland, Ohio, USA.
Sheen CherianDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio, USA.
Arun D SinghDepartment of Ophthalmic Oncology, Cole Eye Institute, Cleveland, Ohio, USA.
Cleveland Eye Clinic · USCancer Institute (WIA) · INCase Western Reserve University · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to report outcomes following radiation therapy in patients with biopsy-proven extranodal marginal zone lymphoma of the ocular adnexa and uvea.

methodsRecords from a single institution were retrospectively reviewed from January 1997 to December 2015. The mean follow-up duration was 38 months (range 0-194). Radiation therapy was administered to 77 eyes (60 patients); 57 of the 77 eyes (74%) were treated with radiation only (range 20-36 Gy, median 15 fractions). Radiation cataract, radiation retinopathy, and optic neuropathy assessments were performed on all eyes treated with radiation.

results100% of the 47 patients treated with radiation therapy only had local control with an average dose of 26.5 Gy (median 25.2 [range 20-36] Gy; 150-200 cGy per fraction). Four patients lost 2 lines or more of vision after radiation. The most common complication of radiation therapy was cataract formation/progression in 19 eyes (25%). Radiation retinopathy was observed only in 1 patient (1%).

conclusionOur results confirm that radiation therapy (median 25 Gy) for extranodal marginal zone lymphoma of the ocular adnexa is associated with high local control and low risk of visually significant complications.

Indexed as

Adnexal tumorsLymphomaRadiation damage

Identifiers

PMID29134184
PMCPMC5675111
OpenAlexW2587098046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.