Evidence map›Paper›PMID 29133922›Full record

ArticleScientific reports2017

Essential role of mitochondrial Stat3 in p38

Xinlai Cheng, Christiane Peuckert, Stefan Wölfl

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

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  5. Radiation-sensitive circRNA promotes intestinal regeneration.Cellular & molecular biology letters · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Xinlai ChengInstitut für Pharmazie und Molekulare Biotechnologie, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 364, 69120, Heidelberg, Germany. x.cheng@uni-heidelberg.de.ORCID 0000-0001-6441-3742
Christiane PeuckertDepartment of Organismal Biology, Uppsala University, Uppsala, S-75236, Sweden.
Stefan WölflInstitut für Pharmazie und Molekulare Biotechnologie, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 364, 69120, Heidelberg, Germany.
Heidelberg University · DEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stat3 is an oncogene, frequently associated with malignant transformation. A body of evidence implicates that phospho-Stat3

Indexed as

ApoptosisMAP Kinase Signaling SystemOxidative StressAmino Acid SubstitutionHEK293 CellsHeLa CellsHumansMAP Kinase Kinase Kinase 5MitochondriaMutation, MissenseNeoplasmsOncogene Proteinsp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesSTAT3 Transcription FactorMAP3K5 protein, humanMAP Kinase Kinase Kinase 5Oncogene Proteinsp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesSTAT3 protein, humanSTAT3 Transcription Factor

Identifiers

PMID29133922
PMCPMC5684365
OpenAlexW2767986209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.