ArticleScientific reports2017
Impact of spatial characteristics in the left stenotic coronary artery on the hemodynamics and visualization of 3D replica models.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Decoding triple negative breast cancer bone metastasis: from 3D bioprinted models to clinical translation.Journal of nanobiotechnology · 2026Review
- Physiology-guided beat-level arrhythmia classification from ECG using a CNN-transformer hybrid neural network.Frontiers in cardiovascular medicine · 2026Article
- Deep learning-assisted 3D CT angiography for supply-vessel localization in inflammatory peripheral pulmonary artery pseudoaneurysms.Frontiers in medicine · 2026Article
- Simulation-based machine learning for real-time assessment of side-branch hemodynamics in coronary bifurcation lesions.The international journal of high performance computing applications · 2025Article
- Cardiovascular Tissue Engineering Models for Atherosclerosis Treatment Development.Bioengineering (Basel, Switzerland) · 2023Review
- Understanding Atherosclerosis Pathophysiology: Can Additive Manufacturing Be Helpful?Polymers · 2023Review
- Breast MRI Segmentation and Ki-67 High- and Low-Expression Prediction Algorithm Based on Deep Learning.Computational and mathematical methods in medicine · 2022Article
- Point-of-care 3D printing: a low-cost approach to teaching carotid artery stenting.3D printing in medicine · 2021Article
- Clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: adult cardiac conditions.3D printing in medicine · 2020Article
- Coronary arteries hemodynamics: effect of arterial geometry on hemodynamic parameters causing atherosclerosis.Medical & biological engineering & computing · 2020Article
- 3D Printed Biomodels for Flow Visualization in Stenotic Vessels: An Experimental and Numerical Study.Micromachines · 2020Article
- PIV investigation of the flow fields in subject-specific vertebro-basilar (VA-BA) junction.Biomedical engineering online · 2019Article
- A cationic near infrared fluorescent agent and ethyl-cinnamate tissue clearing protocol for vascular staining and imaging.Scientific reports · 2019Article
- Health risk stratification based on computed tomography pulmonary artery obstruction index for acute pulmonary embolism.Scientific reports · 2018Article
- Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios.3D printing in medicine · 2018Article
- Numerical analysis of the pressure drop across highly-eccentric coronary stenoses: application to the calculation of the fractional flow reserve.Biomedical engineering online · 2018Article
- Clinical validation and assessment of aortic hemodynamics using computational fluid dynamics simulations from computed tomography angiography.Biomedical engineering online · 2018Article
- Observational
- A new CFD based non-invasive method for functional diagnosis of coronary stenosis.Biomedical engineering online · 2018Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease has been the major cause of death worldwide. Although the initiation and progression mechanism of the atherosclerosis are similar, the stenotic characteristics and the corresponding medical decisions are different between individuals. In the present study, we performed anatomic and hemodynamic analysis on 8 left coronary arterial trees with 10 identified stenoses. A novel boundary condition method had been implemented for fast computational fluid dynamics simulations and patient-specific three-dimensional printed models had been built for visualizations. Our results suggested that the multiple spatial characteristics (curvature of the culprit vessel multiplied by an angle of the culprit's vessel to the upstream parent branch) could be an index of hemodynamics significance (r = -0.673, P-value = 0.033). and reduction of the maximum velocity from stenosis to downstream was found correlated to the FFRCT (r = 0.480, p = 0.160). In addition, 3D printed models could provide accurate replicas of the patient-specific left coronary arterial trees compare to virtual 3D models (r = 0.987, P-value < 0.001). Therefore, the visualization of the 3D printed models could help understand the spatial distribution of the stenoses and the hand-held experience could potentially benefit the educating and preparing of medical strategies.
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