ArticleScientific reports2017
Cold acclimation causes fiber type-specific responses in glucose and fat metabolism in rat skeletal muscles.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Exercise and cold exposure as dual physiological stressors in MASLD: AMPK-mediated metabolic adaptation and interorgan crosstalk.Frontiers in physiology · 2026Review
- Acute Cold Exposure Cell-Autonomously Reduces mTORC1 Signaling and Protein Synthesis Independent of AMPK.Cells · 2025Article
- Huddling behavior regulate adaptive thermogenesis in Brandt's voles (Lasiopodomys brandtii).Cell & bioscience · 2025Article
- Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy.BMC biology · 2023Article
- Appropriate cold stimulation changes energy distribution to improve stress resistance in broilers.Journal of animal science · 2023Article
- Transcriptome analysis revealed potential genes involved in thermogenesis in muscle tissue in cold-exposed lambs.Frontiers in genetics · 2022Article
- Single-cell RNA sequencing and lipidomics reveal cell and lipid dynamics of fat infiltration in skeletal muscle.Journal of cachexia, sarcopenia and muscle · 2021Article
- Physiological Effects of Intermittent Passive Exposure to Hypobaric Hypoxia and Cold in Rats.Frontiers in physiology · 2021Article
- Multiple Roles in Neuroprotection for the Exercise Derived Myokine Irisin.Frontiers in aging neuroscience · 2021Review
- Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice.International journal of molecular sciences · 2019Article
- Metabolic adaptation and maladaptation in adipose tissue.Nature metabolism · 2019Review
- Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle.Cell reports · 2018Article
- Circulating fibroblast growth factor 21 is reduced, whereas its production is increased in a fat depot-specific manner in cold-acclimated rats.Adipocyte · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated fiber type-specific metabolic responses and the molecular mechanisms that regulate glucose and fat metabolism in oxidative and glycolytic muscles upon cold acclimation. Male Wistar rats were exposed to cold (4 °C) for 7 days, and then glycogen synthesis and content, glucose and palmitate oxidation, and the molecular mechanisms underlying these metabolic pathways were assessed in soleus (Sol), extensor digitorum longus (EDL), and epitrochlearis (Epit) muscles. Cold acclimation increased glycogen synthesis, glycogen content, glucose oxidation, and reduced glycogen synthase (GS) phosphorylation only in Sol muscles. Protein kinase B (AKT), glycogen synthase kinase 3 (GSK3), and AMP-activated protein kinase (AMPK) phosphorylation increased in all three muscles upon cold acclimation. Cold acclimation increased palmitate oxidation, gene expression of the transcriptional co-activator Pgc-1α, lipoprotein lipase (Lpl), fatty acid transporter (Cd36), and Sarco/endoplasmic reticulum Ca
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