Evidence map›Paper›PMID 29133854›Full record

ArticleScientific reports2017

Copper (II) binding of NAD(P)H- flavin oxidoreductase (NfoR) enhances its Cr (VI)-reducing ability.

Huawen Han, Zhenmin Ling, Tuoyu Zhou, Rong Xu, Yongxing He, Pu Liu, Xiangkai Li

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. NfoR: Chromate Reductase or Flavin Mononucleotide Reductase?Applied and environmental microbiology · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huawen HanMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China.
Zhenmin LingMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China.
Tuoyu ZhouMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China.
Rong XuMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China.
Yongxing HeMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China.
Pu LiuDepartment of Development Biology Sciences, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China.
Xiangkai LiMinistry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, Gansu, 730000, People's Republic of China. xkli@lzu.edu.cn.ORCID 0000-0003-2931-7565

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes can reduce hexavalent chromium Cr (VI) to the less toxic and soluble trivalent Cr (III). Copper stimulates microbial reduction of Cr (VI) by the Bacillus, Ochrobactrum, and Gluconobacter species; however, the mechanism remains unclear. In our study, the rate of Cr (VI) reduction by Staphylococcus aureus LZ-01 was increased by 210 % when supplemented with 60 μM Cu (II). A putative NAD(P)H-flavin oxidoreductase gene (nfoR) was upregulated under Cr (VI) stress. NfoR-knockout mutant displayed impaired reduction of Cr (VI) and Cu (II)-enhanced Cr (VI) reduction by nfoR isogenic mutant was attenuated in the presence of Cu (II). In vitro tests showed an increased V

Indexed as

Bacterial ProteinsBiocatalysisBiodegradation, EnvironmentalCarcinogens, EnvironmentalChromiumCoenzymesCopperFMN ReductaseGeologic SedimentsOxidation-ReductionStaphylococcus aureusBacterial ProteinsCarcinogens, EnvironmentalChromiumchromium hexavalent ionCoenzymesCopperFMN Reductase

Identifiers

PMID29133854
PMCPMC5684319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.