Observational studyScientific reports2017
Incidence of asymptomatic neurosyphilis in serofast Chinese syphilis patients.
Observational study in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Risk factors of serofast state in patients undergoing syphilis: a meta-analysis of 17 cohort studies.Frontiers in immunology · 2025Pooled it
- Management of Adult Syphilis: Key Questions to Inform the 2021 Centers for Disease Control and Prevention Sexually Transmitted Infections Treatment Guidelines.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Pooled it
- Neurosyphilis in China: A Systematic Review of Cases From 2009-2021.Frontiers in medicine · 2022Pooled it
- Diagnostic tools for neurosyphilis: a systematic review.BMC infectious diseases · 2021Pooled it
- The prevalence of asymptomatic neurosyphilis among HIV-negative serofast patients in China: A meta-analysis.PloS one · 2020Pooled it
- Clinical and Laboratory Characteristics of Symptomatic and Asymptomatic Neurosyphilis in HIV-Negative Patients: A Retrospective Study of 264 Cases.BioMed research international · 2019Trial
- Serofast Syphilis Is Associated with Phospholipid-Dependent Coagulation Abnormalities and B-Cell Activation Following Treatment.International journal of molecular sciences · 2026Article
- Analysis of influencing factors for syphilis serofast and development and evaluation of a predictive model.Frontiers in immunology · 2026Article
- Diagnostic importance of Treponema pallidum Tp0971 in the serological assessment of treatment efficacy for syphilis.Annals of clinical microbiology and antimicrobials · 2025Article
- Serofast state after syphilis treatment: implications and recommendations for clinical practice. Narrative review.Postepy dermatologii i alergologii · 2025Review
- Evaluation of cerebrospinal fluid treponema pallidum particle agglutination assay titer for neurosyphilis diagnosis among HIV-negative syphilis patients.Frontiers in immunology · 2025Article
- Selective attention function impairment in HIV-negative patients with early forms of neurosyphilis.European journal of medical research · 2024Article
- Article
- Cerebrospinal Fluid Biomarkers of Symptomatic Neurosyphilis in People With HIV Compared with Uninfected Individuals.Journal of neurovirology · 2024Article
- Clinical and laboratory features of neurosyphilis: A single-center, retrospective study of 402 patients.Heliyon · 2024Article
- Clinical features associated with neurosyphilis in people living with HIV and late latent syphilis.International journal of STD & AIDS · 2022Article
- Changes of serofast status in HIV negative asymptomatic neurosyphilis patients after treatment.Frontiers in medicine · 2022Article
- CARE-NS, a research strategy for neurosyphilis.Frontiers in medicine · 2022Article
- Positive syphilis serology contributes to intracranial stenosis in ischemic stroke patients.Brain and behavior · 2021Article
- Clinical Manifestations, Fluid Changes and Neuroimaging Alterations in Patients with General Paresis of the Insane.Neuropsychiatric disease and treatment · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More new diagnosed syphilis cases were reported in china, the incidence and relevant factors of asymptomatic neurosyphilis (ANS) in serofast syphilis patients were unclear. Clinical and laboratory data of 402 Human Immunodeficiency Virus (HIV) negative, serofast syphilis patients, who underwent lumbar puncture at the Peking University Ditan Teaching Hospital between September 2008 and August 2016, were collected. Incidence of ANS was verified and the relevant factors were further analyzed. According to the ANS criteria, 139 (34.6%) patients had ANS. Of these, 40 (28.8%) had reactive cerebrospinal fluid (CSF), rapid plasma reagin (RPR) positive, 115 (82.7%) had CSF white blood cell (WBC) count > 5 × 10
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.