Evidence map›Paper›PMID 29133599›Full record

ArticleCirculation2018

Potential US Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline.

Paul Muntner, Robert M Carey, Samuel Gidding, Daniel W Jones, Sandra J Taler, Jackson T Wright, Paul K Whelton

2 registry-linked trialsAbstract read
In one paragraph

Article in Circulation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 364 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
364citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03588520 naunknown statusnot on this map

Investigation Of The Utility Of Home Blood Pressure Measurements Towards Improving The Management Of Hypertension In Patients In Stage 3 And 4 Chronic Kidney Disease

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2018 to 2022Enrolled70ConditionsHypertension, Chronic Kidney DiseasesArmsHome Blood Pressure Monitoring
NCT04908982 phase4unknown statusnot on this mapstarted 2021, after this paper: background citation

Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension: A Pilot Study

TypeinterventionalSponsorEastern Virginia Medical SchoolRan2021 to 2023Enrolled60ConditionsPre-EclampsiaArmsAspirin 81mg
3 · Its place in the literature

Who cites it

364 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Evening versus morning dosing regimen drug therapy for hypertension.The Cochrane database of systematic reviews · 2024
    Pooled it
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  4. A Systematic Review and Meta-analysis of the Clinical and Epidemiological Characteristics of Patients with Hypertensive Emergencies: Implication for Risk Stratification.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Pooled it
  5. Pooled it
  6. [Integrated Care Protocol: Hypertension].Revista medica del Instituto Mexicano del Seguro Social · 2022
    Guideline
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Trial
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  15. Pharmacist-Directed Self-Management of Blood Pressure Versus Conventional Management in Patients with Hypertension: A Randomized Control Trial.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021
    Trial
  16. Trial
  17. Article
  18. Article
  19. Article
  20. Dynamic [Research square · 2026
    Article

304 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama (P.W.) pmuntner@uab.edu.
Robert M CareyDepartment of Medicine, University of Virginia, Charlottesville, Virginia (R.M.C.).
Samuel GiddingNemours Cardiac Center, A. I. DuPont Hospital for Children, Wilmington, Delaware (S.G.).
Daniel W JonesDepartment of Medicine, University of Mississippi, Jackson, Mississippi (D.W.J.).
Sandra J TalerDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota (S.J.T.).
Jackson T WrightDivision of Nephrology and Hypertension, University Hospitals of Cleveland Medical Center, Cleveland, Ohio (J.T.W.).
Paul K WheltonDepartment of Epidemiology, Tulane University, New Orleans, Louisiana (P.K.W.).

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI JONES, ALAN E · 2016 to 2025
$38.2M
Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAREY, ROBERT MUNSON · 2004 to 2020
$31.8M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Visit-to-visit variability of blood pressure and CVD and renal outcomesR01HL110993 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MUNTNER, PAUL · 2012 to 2014
$1.1M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL110993NHLBI NIH HHS R01 HL117323NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

backgroundThe 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults provides recommendations for the definition of hypertension, systolic and diastolic blood pressure (BP) thresholds for initiation of antihypertensive medication, and BP target goals.

objectivesThis study sought to determine the prevalence of hypertension, implications of recommendations for antihypertensive medication, and prevalence of BP above the treatment goal among US adults using criteria from the 2017 ACC/AHA guideline and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7).

methodsThe authors analyzed data from the 2011 to 2014 National Health and Nutrition Examination Survey (N = 9 623). BP was measured 3 times following a standardized protocol and averaged. Results were weighted to produce US population estimates.

resultsAccording to the 2017 ACC/AHA and JNC7 guidelines, the crude prevalence of hypertension among US adults was 45.6% (95% confidence interval [CI]: 43.6% to 47.6%) and 31.9% (95% CI: 30.1% to 33.7%), respectively, and antihypertensive medication was recommended for 36.2% (95% CI: 34.2% to 38.2%) and 34.3% (95% CI: 32.5% to 36.2%) of US adults, respectively. Nonpharmacological intervention is advised for the 9.4% of US adults with hypertension who are not recommended for antihypertensive medication according to the 2017 ACC/AHA guideline. Among US adults taking antihypertensive medication, 53.4% (95% CI: 49.9% to 56.8%) and 39.0% (95% CI: 36.4% to 41.6%) had BP above the treatment goal according to the 2017 ACC/AHA and JNC7 guidelines, respectively.

conclusionsCompared with the JNC7 guideline, the 2017 ACC/AHA guideline results in a substantial increase in the prevalence of hypertension, a small increase in the percentage of US adults recommended for antihypertensive medication, and more intensive BP lowering for many adults taking antihypertensive medication.

Indexed as

American Heart AssociationAdultAgedAntihypertensive AgentsBlood PressureCardiologyFemaleHumansHypertensionMaleMiddle AgedNutrition SurveysPractice Guidelines as TopicPrevalenceRisk FactorsTime FactorsAntihypertensive Agentshypertensionprevalencetreatment

Identifiers

PMID29133599
PMCPMC5873602

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.