Evidence map›Paper›PMID 29133578›Full record

ArticleBMJ case reports2017

Orlistat-induced oxalate nephropathy: an under-recognised cause of chronic kidney disease.

Laurence Richard Solomon, Andrew Christopher Nixon, Leanne Ogden, Beena Nair

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Case - Orlistat-induced calcium oxalate crystalluria.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  6. Oxalate crystal-related acute renal injury caused by orlistat: A case report.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  7. Management of Obesity in Adults with CKD.Journal of the American Society of Nephrology : JASN · 2021
    Review
  8. Review
  9. The association of calcium oxalate deposition in kidney allografts with graft and patient survival.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020
    Article
  10. Review
  11. Secondary Oxalate Nephropathy: A Systematic Review.Kidney international reports · 2018
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laurence Richard SolomonDepartment of Renal Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Andrew Christopher NixonDepartment of Renal Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Leanne OgdenDepartment of Renal Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Beena NairDepartment of Histopathology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Lancashire Teaching Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two patients developed kidney failure due to oxalate deposition in the kidney while taking orlistat. Cessation of orlistat was followed by partial recovery of kidney function. The mechanism by which orlistat causes hyperoxaluria and the management of orlistat-induced oxalate nephropathy is reviewed. We suggest that all patients taking orlistat are at risk of this condition, which may develop insidiously and is easily overlooked. Monitoring of kidney function of patients taking orlistat is warranted.

Indexed as

AgedAnti-Obesity AgentsCalcium OxalateFemaleHumansHyperoxaluriaKidney Tubular Necrosis, AcuteLactonesMaleMicroscopyObesityOrlistatRenal Insufficiency, ChronicAnti-Obesity AgentsCalcium OxalateLactonesOrlistatAcute Renal FailureContraindications And PrecautionsMetabolic DisordersObesity (nutrition)Renal System

Identifiers

PMID29133578
PMCPMC5695294
OpenAlexW2770397886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.