Evidence map›Paper›PMID 29133550›Full record

ArticleAntimicrobial agents and chemotherapy2018

Discovery of New Inhibitors of Toxoplasma gondii via the Pathogen Box.

Jérémy Spalenka, Sandie Escotte-Binet, Ali Bakiri, Jane Hubert, Jean-Hugues Renault, Frédéric Velard, Simon Duchateau, Dominique Aubert, Antoine Huguenin, Isabelle Villena

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
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  6. Pentamidine inhibition of streptopain attenuatesbioRxiv : the preprint server for biology · 2025
    Article
  7. Novel drug candidates targetingFrontiers in pharmacology · 2025
    Article
  8. Article
  9. Cloning, expression, and purification of an α-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
  10. Amoebicidal Effect of COVID Box Molecules againstPharmaceuticals (Basel, Switzerland) · 2024
    Article
  11. Modulation of CXCL10 activity as a therapeutic target of ocular toxoplasmosis in diabetic mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  12. Generation of MatureBio-protocol · 2024
    Article
  13. Article
  14. Article
  15. Anti-Parasitology · 2023
    Article
  16. Article
  17. Evaluation of the Anti-Antibiotics (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jérémy SpalenkaLaboratoire de Parasitologie-Mycologie, EA 3800, SFR CAP-Santé FED 4231, Centre Hospitalier de Reims et Université de Reims Champagne-Ardenne, Reims Cedex, France.
Sandie Escotte-BinetLaboratoire de Parasitologie-Mycologie, EA 3800, SFR CAP-Santé FED 4231, Centre Hospitalier de Reims et Université de Reims Champagne-Ardenne, Reims Cedex, France.
Ali BakiriUMR CNRS 7312, Université de Reims Champagne-Ardenne, Reims Cedex 2, France.
Jane HubertUMR CNRS 7312, Université de Reims Champagne-Ardenne, Reims Cedex 2, France.
Jean-Hugues RenaultUMR CNRS 7312, Université de Reims Champagne-Ardenne, Reims Cedex 2, France.
Frédéric VelardBiomatériaux et Inflammation en site Osseux, EA 4691, Université de Reims Champagne-Ardenne, Reims Cedex, France.
Simon DuchateauLaboratoire de Parasitologie-Mycologie, EA 3800, SFR CAP-Santé FED 4231, Centre Hospitalier de Reims et Université de Reims Champagne-Ardenne, Reims Cedex, France.
Dominique AubertLaboratoire de Parasitologie-Mycologie, EA 3800, SFR CAP-Santé FED 4231, Centre Hospitalier de Reims et Université de Reims Champagne-Ardenne, Reims Cedex, France.
Antoine HugueninLaboratoire de Parasitologie-Mycologie, EA 3800, SFR CAP-Santé FED 4231, Centre Hospitalier de Reims et Université de Reims Champagne-Ardenne, Reims Cedex, France.
Isabelle VillenaLaboratoire de Parasitologie-Mycologie, EA 3800, SFR CAP-Santé FED 4231, Centre Hospitalier de Reims et Université de Reims Champagne-Ardenne, Reims Cedex, France ivillena@chu-reims.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntiparasitic AgentsCell LineChlorocebus aethiopsInhibitory Concentration 50Structure-Activity RelationshipToxoplasmaToxoplasmosisVero CellsAntiparasitic Agentsantitoxoplasmic activityantitoxoplasmic compounddrug screeningPathogen BoxToxoplasma gondii

Identifiers

PMID29133550
PMCPMC5786798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.