Evidence map›Paper›PMID 29133496›Full record

ArticleAnnals of family medicine2017

Factors Influencing Allopurinol Initiation in Primary Care.

Lorna E Clarson, Samantha L Hider, John Belcher, Edward Roddy, Christian D Mallen

Open access · diamondAbstract read
In one paragraph

Article in Annals of family medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lorna E ClarsonResearch Institute for Primary Care & Health Sciences, Keele University, Keele, Staffordshire, United Kingdom l.clarson@keele.ac.uk.
Samantha L HiderResearch Institute for Primary Care & Health Sciences, Keele University, Keele, Staffordshire, United Kingdom.
John BelcherResearch Institute for Primary Care & Health Sciences, Keele University, Keele, Staffordshire, United Kingdom.
Edward RoddyResearch Institute for Primary Care & Health Sciences, Keele University, Keele, Staffordshire, United Kingdom.
Christian D MallenResearch Institute for Primary Care & Health Sciences, Keele University, Keele, Staffordshire, United Kingdom.
Keele University · GB

Funding

Department of Health RP_2014-04-026
6 · The paper itself

Abstract

Despite guidance on appropriate initiation, urate-lowering therapy is prescribed for only a minority of patients with gout. Electronic health records for 8,142 patients with gout were used to investigate the effect of age, sex, comorbidities, number of consultations, and meeting internationally agreed eligibility criteria on time to allopurinol initiation. Time to first prescription was modeled using multilevel Cox proportional hazards regression. Allopurinol initiation was positively associated with meeting eligibility criteria at diagnosis of gout, but negatively associated with becoming eligible after diagnosis. Managing gout as a chronic disease, with regular reviews to discuss allopurinol treatment, may reduce barriers to treatment.

Indexed as

Time-to-TreatmentAgedAllopurinolComorbidityElectronic Health RecordsFemaleGoutGout SuppressantsHumansMaleMiddle AgedPrimary Health CareProportional Hazards ModelsUnited KingdomAllopurinolGout Suppressantsallopurinolgoutprimary care

Identifiers

PMID29133496
PMCPMC5683869
OpenAlexW2770988310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.