Evidence map›Paper›PMID 29133396›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells.

A Ripamonti, E Provasi, M Lorenzo, M De Simone, V Ranzani, S Vangelisti, S Curti, R J P Bonnal, L Pignataro, S Torretta and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
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  13. Review
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  15. Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Review
  17. Non-Coding RNAs in CD4Frontiers in immunology · 2020
    Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

A RipamontiIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
E ProvasiIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
M LorenzoIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
M De SimoneIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
V RanzaniIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
S VangelistiIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
S CurtiIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
R J P BonnalIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
L PignataroDepartment of Otolaryngology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Cà Granda Ospedale Maggiore Policlinico, Milan 20122, Italy.
S TorrettaDepartment of Otolaryngology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Cà Granda Ospedale Maggiore Policlinico, Milan 20122, Italy.
J GeginatIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.
G RossettiIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy.ORCID 0000-0001-6361-311X
M PaganiIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy; abrignani@ingm.org pagani@ingm.org.
S AbrignaniIstituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan 20122, Italy; abrignani@ingm.org pagani@ingm.org.ORCID 0000-0002-0794-3285
Istituto Nazionale Genetica Molecolare · ITUniversity of Milan · IT

Funding

European Research Council 269022European Research Council 617978
6 · The paper itself

Abstract

Follicular helper T cells (T

Indexed as

Adaptive ImmunityAnimalsB-LymphocytesCD40 LigandCell DifferentiationGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksGerminal CenterHumansMiceMice, Inbred C57BLMicroRNAsPrimary Cell CulturePromoter Regions, GeneticProtein BindingBCL6 protein, humanCD40 LigandMicroRNAsMIRN31 microRNA, humanProto-Oncogene Proteins c-bcl-6SH2D1A protein, humanSignaling Lymphocytic Activation Molecule Associated ProteinBCL6human CD4+ TFHmicroRNARNA-seqtranscriptional regulation

Identifiers

PMID29133396
PMCPMC5715737
OpenAlexW2770320321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.