ArticleInfection and immunity2018
Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways.
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Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 24 citations in OpenAlex.
- IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice.Nature microbiology · 2026Article
- Rotavirus mucosal immunology: insights and research priorities from an international convening in Liverpool, March 2024.NPJ vaccines · 2026Article
- IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice.bioRxiv : the preprint server for biology · 2026Article
- Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens.Nature communications · 2025Article
- Dynamics of IgM and IgA Antibody Response Profile AgainstInternational journal of molecular sciences · 2025Article
- Article
- The intersection between host-pathogen interactions and metabolism during Vibrio cholerae infection.Current opinion in microbiology · 2024Review
- Review
- B-Cell Epitope Mapping of theInternational journal of molecular sciences · 2022Article
- Microbiota-Associated Biofilm Regulation Leads toFrontiers in cellular and infection microbiology · 2022Article
- Correlates of Protection for Cholera.The Journal of infectious diseases · 2021Article
- Innate Immunity as an Executor of the Programmed Death of Individual Organisms for the Benefit of the Entire Population.International journal of molecular sciences · 2021Review
- Systemic, Mucosal, and Memory Immune Responses following Cholera.Tropical medicine and infectious disease · 2021Review
- Mutual interaction of microbiota and host immunity during health and diseases.Biophysics reports · 2021Article
- Gut Microbiota and Development of Vibrio cholerae-Specific Long-Term Memory B Cells in Adults after Whole-Cell Killed Oral Cholera Vaccine.Infection and immunity · 2021Article
- DksA coordinates bile-mediated regulation of virulence-associated phenotypes in type three secretion system-positiveMicrobiology (Reading, England) · 2021Article
- Pathogenicity and virulence regulation ofVirulence · 2020Review
- Bacteria That Cause Enteric Diseases Stimulate Distinct Humoral Immune Responses.Frontiers in immunology · 2020Review
- Virulence Regulation and Innate Host Response in the Pathogenicity ofFrontiers in cellular and infection microbiology · 2020Review
- Review
Corrections and comments
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Authors and funding
19 authors at 4 institutions in 2 countries.
Daniel L BourqueDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Taufiqur Rahman BhuiyanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Diane P GenereuxProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Rasheduzzaman RashuInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Crystal N EllisDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Fahima ChowdhuryInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Ashraful I KhanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Nur Haq AlamInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Anik PaulInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Lazina HossainInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Leslie M Mayo-SmithDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Richelle C CharlesDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Ana A WeilDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Regina C LaRocqueDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Stephen B CalderwoodDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Edward T RyanDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Elinor K KarlssonProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Firdausi Qadri *International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh fqadri@icddrb.org jbharris@mgh.harvard.edu.
Jason B Harris *Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA fqadri@icddrb.org jbharris@mgh.harvard.edu.
International Centre for Diarrhoeal Disease Research · BDMassachusetts General Hospital · USHarvard University · USBroad Institute · US
Funding
INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1MImmune Responses to Vibrio cholerae infection and vaccination in HaitiR01AI099243 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B, IVERS, LOUISE C. · 2012 to 2022
$7.9MTraining program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4MO-Specific Polysaccharide Responses and CholeraR37AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Edward T. Ryan · 2020 to 2026
$5.1MInnate and early B cell responses to V. choleraeR01AI103055 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B · 2014 to 2018
$3.9MO-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7MThe gut microbiome and susceptibility to Vibrio choleraeK08AI123494 · NIAID · UNIVERSITY OF WASHINGTON · PI WEIL, ANA A · 2016 to 2020
$967kO-Specific Polysaccharide Responses and CholeraR56AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2013 to 2020
$843kHigh-throughput proteomic study of protective immunity in human cholera infectionK08AI089721 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C · 2010 to 2014
$684kHumoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359kFIC NIH HHS D43 TW005572FIC NIH HHS K43 TW010362NIAID NIH HHS K08 AI089721NIAID NIH HHS K08 AI123494NIAID NIH HHS R01 AI099243NIAID NIH HHS R01 AI103055NIAID NIH HHS R01 AI106878NIAID NIH HHS R37 AI106878NIAID NIH HHS R56 AI106878NIAID NIH HHS T32 AI007061
Abstract
To better understand the innate immune response to
Indexed as
Immunity, InnateImmunity, MucosalSignal TransductionAdultBiopsyCholeraDuodenumFemaleGene Expression ProfilingHumansMaleVibrio choleraeYoung Adultimmune mechanismsmucosal immunityVibrio cholerae
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.