ArticleJournal of the American Medical Directors Association2018
The Pathophysiology of Frailty: Why Sex Is So Important.
Article in Journal of the American Medical Directors Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Sex Differences in the Association Between Inflammatory Biomarkers (Hs-CRP, IL-6, IL-10, TNF-α) and Frailty in Hospitalized Adults Aged ≥65 in Taizhou, China: A Cross-Sectional Study.Clinical interventions in aging · 2025Article
- Baseline Characteristics of Frailty and Disease Stage in Older People Living With CKD.Kidney international reports · 2025Article
- Assessment of Frailty Among Older Adults in the Physical Activity Daily Trial.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Observational
- Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study.BMC geriatrics · 2023Article
- Frailty as a predictor of mortality: a comparative cohort study of older adults in Costa Rica and the United States.BMC public health · 2023Article
- Frailty: the perioperative and anesthesia challenges of an emerging pandemic.Journal of anesthesia · 2023Review
- Biological Frailty Index in centenarians.Aging clinical and experimental research · 2022Article
- Frailty Status Among the Elderly of Different Genders and the Death Risk: A Follow-Up Study.Frontiers in medicine · 2021Article
- Phenotypic Frailty Assessment in Mice: Development, Discoveries, and Experimental Considerations.Physiology (Bethesda, Md.) · 2020Review
- Age and life expectancy clocks based on machine learning analysis of mouse frailty.Nature communications · 2020Article
- Vitamin D Receptor Polymorphisms in Sex-Frailty Paradox.Nutrients · 2020Article
- Article
- Chronic Treatment With the ACE Inhibitor Enalapril Attenuates the Development of Frailty and Differentially Modifies Pro- and Anti-inflammatory Cytokines in Aging Male and Female C57BL/6 Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Frailty effects on non-demented cognitive trajectories are moderated by sex and Alzheimer's genetic risk.Alzheimer's research & therapy · 2019Article
- A Murine Frailty Index Based on Clinical and Laboratory Measurements: Links Between Frailty and Pro-inflammatory Cytokines Differ in a Sex-Specific Manner.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
29133018What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.