Evidence map›Paper›PMID 29132992›Full record

ArticleVaccine2017

Measuring the timeliness of childhood vaccinations: Using cohort data and routine health records to evaluate quality of immunisation services.

Suzanne Walton, Mario Cortina-Borja, Carol Dezateux, Lucy J Griffiths, Karen Tingay, Ashley Akbari, Amrita Bandyopadhyay, Ronan A Lyons, Helen Bedford

Abstract read
In one paragraph

Article in Vaccine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Suzanne WaltonPopulation, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
Mario Cortina-BorjaPopulation, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
Carol DezateuxPopulation, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
Lucy J GriffithsPopulation, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
Karen TingayFarr Institute, Swansea University Medical School, Wales SA2 8PP, UK.
Ashley AkbariFarr Institute, Swansea University Medical School, Wales SA2 8PP, UK.
Amrita BandyopadhyayFarr Institute, Swansea University Medical School, Wales SA2 8PP, UK.
Ronan A LyonsFarr Institute, Swansea University Medical School, Wales SA2 8PP, UK.
Helen BedfordPopulation, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK. Electronic address: h.bedford@ucl.ac.uk.

Funding

British Heart FoundationCancer Research UKMedical Research Council MC_PC_13043Medical Research Council MR/K006525/1Medical Research Council MR/K006584/1Medical Research Council MR/K023233/1Wellcome TrustWellcome Trust 087389/B/08/Z
6 · The paper itself

Abstract

backgroundTo achieve full benefits of vaccination programmes, high uptake and timely receipt of vaccinations are required.

objectivesTo examine uptake and timeliness of infant and pre-school booster vaccines using cohort study data linked to health records.

methodsWe included 1782 children, born between 2000 and 2001, participating in the Millennium Cohort Study and resident in Wales, whose parents gave consent for linkage to National Community Child Health Database records at the age seven year contact. We examined age at receipt, timeliness of vaccination (early, on-time, delayed, or never), and intervals between vaccine doses, based on the recommended schedule for children at that time, of the following vaccines: primary (diphtheria, tetanus, pertussis (DTP), polio, Meningococcal C (Men C), Haemophilus influenzae type b (Hib)); first dose of measles, mumps and rubella (MMR); and pre-school childhood vaccinations (DTP, polio, MMR). We compared parental report with child health recorded MMR vaccination status at age three years.

resultsWhile 94% of children received the first dose of primary vaccines early or on time, this was lower for subsequent doses (82%, 65% and 88% for second and third doses and pre-school booster respectively). Median intervals between doses exceeded the recommended schedule for all but the first dose with marked variation between children. There was high concordance (97%) between parental reported and child health recorded MMR status.

conclusionsRoutine immunisation records provide useful information on timely receipt of vaccines and can be used to assess the quality of childhood vaccination programmes. Parental report of MMR vaccine status is reliable.

Indexed as

Health Records, PersonalChildChild HealthChild, PreschoolCohort StudiesDatabases, FactualDiphtheria-Tetanus-Pertussis VaccineFemaleHaemophilus VaccinesHumansImmunization ProgramsImmunization ScheduleImmunization, SecondaryInfantMaleMeasles-Mumps-Rubella VaccineDiphtheria-Tetanus-Pertussis VaccineHaemophilus VaccinesMeasles-Mumps-Rubella VaccineChildChild health systemsMillennium Cohort Study (MCS)TimelinessVaccination

Identifiers

PMID29132992
PMCPMC5720480

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.