Evidence map›Paper›PMID 29132400›Full record

ArticleAIDS research and therapy2017

Hospitalization causes and outcomes in HIV patients in the late antiretroviral era in Colombia.

María Fernanda Álvarez Barreneche, Carlos Andrés Restrepo Castro, Alicia Hidrón Botero, Juan Pablo Villa Franco, Ivan Mauricio Trompa Romero, Laura Restrepo Carvajal, Alejandro Eusse García, Adriana Ocampo Mesa, Lina María Echeverri Toro, Glenys Patricia Porras Fernández de Castro and 2 more

Abstract read
In one paragraph

Article in AIDS research and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. [Hospital admission and mortality causes of HIV patients in a third level hospital].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019
    Observational
  13. Article
  14. Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

María Fernanda Álvarez BarrenecheSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia. mariafda_12@hotmail.com.
Carlos Andrés Restrepo CastroSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia.
Alicia Hidrón BoteroSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia.
Juan Pablo Villa FrancoSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia.
Ivan Mauricio Trompa RomeroDivision of Infectious Diseases, Department of Internal Medicine, IPS Universitaria Clínica León XIII, Antioquia, Medellín, Colombia.
Laura Restrepo CarvajalSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia.
Alejandro Eusse GarcíaSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia.
Adriana Ocampo MesaDivision of Infectious Diseases, Department of Internal Medicine, Centros Especializados San Vicente Fundación, Antioquia, Rionegro, Colombia.
Lina María Echeverri ToroDivision of Infectious Diseases, Department of Internal Medicine, Centros Especializados San Vicente Fundación, Antioquia, Rionegro, Colombia.
Glenys Patricia Porras Fernández de CastroDepartment of Internal Medicine, Hospital General de Medellín, Antioquia, Medellín, Colombia.
Jaime Mauricio Ramírez RiveraDivision of Infectious Diseases, Department of Internal Medicine, Centros Especializados San Vicente Fundación, Antioquia, Rionegro, Colombia.
Carlos Andrés Agudelo RestrepoSchool of Health Sciences, Universidad Pontificia Bolivariana, Carrera 44 # 18-56, Antioquia, Medellín, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) has modified the natural history of HIV-infection: the incidence of opportunistic infections (OIs) has decreased and mortality associated to HIV has improved dramatically. The reasons for hospitalization have changed; OIs are no longer the most common reason for admission. This study describes the patient population, admission diagnosis and hospital course of HIV patients in Colombia in the ART era.

methodsPatients admitted with HIV/AIDS at six hospitals in Medellin, Colombia between August 1, 2014 and July 31, 2015 were included. Demographic, laboratory, and clinical data were prospectively collected.

results551 HIV-infected patients were admitted: 76.0% were male, the median age was 37 (30-49). A new diagnosis of HIV was made in 22.0% of patients during the index admission. 56.0% of patients of the entire cohort had been diagnosed with HIV for more than 1 year and 68.9% were diagnosed in an advanced stage of the disease. More than 50.0% of patients had CD4 counts less than 200 CD4 cells/μL and viral loads greater than 100,000 copies. The main reasons for hospital admissions were OIs, tuberculosis, esophageal candidiasis and Toxoplasma encephalitis. The median hospital stay was 14 days (IQR 8-23). Admission to the intensive care unit (ICU) was required in 10.3% of patients and 14.3% were readmitted to the hospital; mortality was 5.4%.

conclusionsSimilar to other countries in the developing world, in Colombia, the leading cause of hospitalization among HIV-infected patients remain opportunistic infections. However, in-hospital mortality was low, similar to those described for high-income countries. Strategies to monitor and optimize the adherence and retention in HIV programs are fundamental to maximize the benefit of ART.

Indexed as

AdultAIDS-Related Opportunistic InfectionsCD4 Lymphocyte CountColombiaCritical CareFemaleHIV InfectionsHospitalizationHospital MortalityHumansLength of StayMaleMiddle AgedViral LoadAcquired immune deficiency syndromeAdherenceAntiretroviralHospitalizationHuman immunodeficiency virusOpportunistic infections

Identifiers

PMID29132400
PMCPMC5683524

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.