ArticleAnnals of clinical microbiology and antimicrobials2017
Intensive care antibiotic consumption and resistance patterns: a cross-correlation analysis.
Article in Annals of clinical microbiology and antimicrobials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 46 citations in OpenAlex.
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- Unveiling the drivers of vancomycin-resistant enterococcus in China: A comprehensive ecological study.Infectious medicine · 2025Article
- Integrating procurement, prescription, and resistance data to strengthen antimicrobial stewardship: insights from a public health institution in India.Frontiers in microbiology · 2025Article
- Insights into the Rising Threat of Carbapenem-Resistant Enterobacterales andAntibiotics (Basel, Switzerland) · 2024Review
- Molecular epidemiology and clinical significance of carbapenemase genes in carbapenem-resistant Acinetobacter baumannii isolates in southern Poland.Polish archives of internal medicine · 2024Article
- Lack of Association between Antimicrobial Consumption and Antimicrobial Resistance in a HIV Preexposure Prophylaxis Population: A Cross-Sectional Study.Antibiotics (Basel, Switzerland) · 2024Article
- Epidemiology of antibiotic consumption and resistance in Mauritius.Frontiers in antibiotics · 2024Article
- Relationship between Antibiotic Consumption and Resistance: A Systematic Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024Review
- The Challenges of The Diagnostic and Therapeutic Approach of Patients with Infectious Pathology in Emergency Medicine.Journal of personalized medicine · 2023Article
- Burden of severe infections due to carbapenem-resistant pathogens in intensive care unit.World journal of clinical cases · 2023Review
- Systematic review of time lag between antibiotic use and rise of resistant pathogens among hospitalized adults in Europe.JAC-antimicrobial resistance · 2023Review
- The Effect of Decreased Antipseudomonal Drug Consumption onAntibiotics (Basel, Switzerland) · 2023Article
- Antibiotic resistance and consumption before and during the COVID-19 pandemic in Valle del Cauca, Colombia.Revista panamericana de salud publica = Pan American journal of public health · 2023Article
- Drug-resistant bacteria in the critically ill: patterns and mechanisms of resistance and potential remedies.Frontiers in antibiotics · 2023Review
- Study on the Detection and Infection Distribution of Multidrug-Resistant Organisms in Different Specimens.Infection and drug resistance · 2022Article
- Trends and Correlation Between Antimicrobial Resistance and Antibiotics Consumption in a Specialist Children's Hospital from 2016 to 2021.Infection and drug resistance · 2022Article
- Microbiological and Clinical Characteristics of Bloodstream Infections in General Intensive Care Unit: A Retrospective Study.Frontiers in medicine · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOver recent decades, a dramatic increase in infections caused by multidrug-resistant pathogens has been observed worldwide. The aim of the present study was to investigate the relationship between local resistance bacterial patterns and antibiotic consumption in an intensive care unit in a Romanian university hospital.
methodsA prospective study was conducted between 1st January 2012 and 31st December 2013. Data covering the consumption of antibacterial drugs and the incidence density for the main resistance phenotypes was collected on a monthly basis, and this data was aggregated quarterly. The relationship between the antibiotic consumption and resistance was investigated using cross-correlation, and four regression models were constructed, using the SPSS version 20.0 (IBM, Chicago, IL) and the R version 3.2.3 packages.
resultsDuring the period studied, the incidence of combined-resistant and carbapenem-resistant P. aeruginosa strains increased significantly [(gradient = 0.78, R
conclusionsThe cross-correlation coefficients and the fitted regression models provide additional evidence that resistance during the a given quarter depends not only on the consumption of antibacterial chemotherapeutic drugs in both that quarter and the previous one, but also on the incidence of resistant strains circulating during the previous quarter.
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