ArticlePLoS genetics2017
The karrikin receptor KAI2 promotes drought resistance in Arabidopsis thaliana.
Article in PLoS genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed, 176 citations in OpenAlex.
- Negative feedback regulation of karrikin signaling inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Discovery of specific rhizosphere bacteriaScience advances · 2026Article
- Overexpression of DWARF14-LIKE2 in Arabidopsis thaliana alters multiple traits related to plant morphology and osmotic and salt stress tolerance.Plant cell reports · 2026Article
- Smoke water and smoke-derived karrikinolide, KARScientific reports · 2026Article
- Desiccation Tolerance in Moss and Liverwort: Insights into the Evolutionary Mechanisms of Terrestrialization.International journal of molecular sciences · 2026Review
- Causal Mediation Analysis of the Effect of Dietary Habits on Sleep Apnea Risk.Combinatorial chemistry & high throughput screening · 2026Article
- Crosstalk between strigolactone and KAI2/KL signalling in plant growth and stress responses.Frontiers in plant science · 2026Review
- Development and Validation of an LC-MS/MS Method for Quantifying Phytohormones Related to Tomato Shelf Life.Foods (Basel, Switzerland) · 2025Article
- Ectopic Expression of a Poplar GenePlants (Basel, Switzerland) · 2025Article
- Role of Plant-Derived Smoke Solution on Plants Under Stress.International journal of molecular sciences · 2025Review
- Chemical application improves stress resilience in plants.Plant molecular biology · 2025Review
- The Multifaceted Impact of Karrikin Signaling in Plants.International journal of molecular sciences · 2025Review
- Strigolactone and karrikin receptors regulate phytohormone biosynthetic and catabolic processes.Plant cell reports · 2025Article
- KAI2-dependent signaling controls vegetative reproduction in Marchantia polymorpha through activation of LOG-mediated cytokinin synthesis (14).Nature communications · 2025Article
- Cotton GhMAX2 promotes single-celled fiber elongation by releasing the GhS1FA-mediated inhibition of fatty acid biosynthesis.Plant cell reports · 2025Article
- Analysis and Functional Prediction of Core Bacteria in theMicroorganisms · 2024Article
- E3 ubiquitin ligase TaSDIR1-4A activates membrane-bound transcription factor TaWRKY29 to positively regulate drought resistance.Plant biotechnology journal · 2024Article
- Karrikin signalling: impacts on plant development and abiotic stress tolerance.Journal of experimental botany · 2024Article
- Identification of osmotic stress resistance mediated byFrontiers in plant science · 2024Article
12 more citing papers are in PubMed but not listed here.
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Authors and funding
19 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drought causes substantial reductions in crop yields worldwide. Therefore, we set out to identify new chemical and genetic factors that regulate drought resistance in Arabidopsis thaliana. Karrikins (KARs) are a class of butenolide compounds found in smoke that promote seed germination, and have been reported to improve seedling vigor under stressful growth conditions. Here, we discovered that mutations in KARRIKIN INSENSITIVE2 (KAI2), encoding the proposed karrikin receptor, result in hypersensitivity to water deprivation. We performed transcriptomic, physiological and biochemical analyses of kai2 plants to understand the basis for KAI2-regulated drought resistance. We found that kai2 mutants have increased rates of water loss and drought-induced cell membrane damage, enlarged stomatal apertures, and higher cuticular permeability. In addition, kai2 plants have reduced anthocyanin biosynthesis during drought, and are hyposensitive to abscisic acid (ABA) in stomatal closure and cotyledon opening assays. We identified genes that are likely associated with the observed physiological and biochemical changes through a genome-wide transcriptome analysis of kai2 under both well-watered and dehydration conditions. These data provide evidence for crosstalk between ABA- and KAI2-dependent signaling pathways in regulating plant responses to drought. A comparison of the strigolactone receptor mutant d14 (DWARF14) to kai2 indicated that strigolactones also contributes to plant drought adaptation, although not by affecting cuticle development. Our findings suggest that chemical or genetic manipulation of KAI2 and D14 signaling may provide novel ways to improve drought resistance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.