ArticleJournal of veterinary internal medicine2018
Cholangitis and Cholangiohepatitis in Dogs: A Descriptive Study of 54 Cases Based on Histopathologic Diagnosis (2004-2014).
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 50 citations in OpenAlex.
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- Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.Journal of medical primatology · 2026Article
- Neutrophilic cholangitis associated with intracholangiocyticVeterinary pathology · 2026Article
- Prevalence, breed predispositions, and culture and sensitivity results of bacterial hepatobiliary infections in dogs in the United Kingdom.Journal of veterinary internal medicine · 2026Article
- Characteristics and outcomes of dogs undergoing cholecystectomy for diseases other than a mature gallbladder mucocele: a retrospective cohort study.Journal of veterinary internal medicine · 2026Article
- Clinical findings and prognostic factors for immediate survival in 33 dogs undergoing surgery for biliary peritonitis.Veterinary surgery : VS · 2025Article
- Comparison of abdominal computed tomography to ultrasonography in the diagnosis of biliary disease in dogs with acute abdominal signs.Frontiers in veterinary science · 2025Article
- Long-Term Survival in Canine Hepatosplenic T-Cell Lymphoma Treated with Toceranib Phosphate Following Splenectomy: A Case of Atypical Lymphoma.Veterinary sciences · 2024Article
- Canine Gallbladder Erosion/Ulcer and Hemocholecyst: Clinicopathological Characteristics of 14 Cases.Animals : an open access journal from MDPI · 2023Article
- Feasibility of Magnetic Resonance Cholangiopancreatography in Dogs-A Post-Mortem Study.Animals : an open access journal from MDPI · 2023Article
- Unusual Case of Biliary Peritonitis in a Dog Secondary to a Gastric Perforation.Veterinary sciences · 2023Article
- Article
- Clinical findings and assessment of factors associated with survival in dogs presenting with hyperbilirubinaemia: 115 cases in Victoria, Australia (2015-2020).Veterinary record open · 2022Article
- Metabolomic serum abnormalities in dogs with hepatopathies.Scientific reports · 2022Article
- Chronic Cholecystitis of Dogs: Clinicopathologic Features and Relationship with Liver.Animals : an open access journal from MDPI · 2021Article
- Changes in Serum Lipid Profiles among Canine Patients Suffering from Chronic Hepatitis.Veterinary sciences · 2021Article
- Risk factors for enterococcal bacteriuria in dogs: A retrospective study.Journal of veterinary internal medicine · 2020Article
- A descriptive study of the histopathologic and biochemical liver test abnormalities in dogs with liver disease in Thailand.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2020Article
- Lifestyle as Risk Factor for Infectious Causes of Death in Young Dogs: A Retrospective Study in Southern Italy (2015-2017).Veterinary medicine international · 2020Article
- Usefulness of noninvasive shear wave elastography for the assessment of hepatic fibrosis in dogs with hepatic disease.Journal of veterinary internal medicine · 2019Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCholangitis in dogs appears to be more common than previously thought, but understanding of the disease remains incomplete.
objectiveTo describe a population of dogs with cholangitis or cholangiohepatitis. ANIMALS: Fifty-four client-owned dogs with cholangitis or cholangiohepatitis.
methodsMedical records of dogs with cholangitis or cholangiohepatitis confirmed by histopathology between January 2004 and December 2014 were identified using a computer-based search and retrospectively reviewed.
resultsClinical signs included vomiting (72.2%), lethargy (70.4%), and inappetence (64.8%). Most dogs (49/50) had increased liver enzyme activities, hyperbilirubinemia (32/50), and hypercholesterolemia (24/43). Ultrasonographic abnormalities of the hepatobiliary system were seen in 84% of cases. On histopathology, 53 of 54 affected dogs had neutrophilic cholangitis (NC) or cholangiohepatitis, whereas 1 dog had lymphocytic cholangitis. Most cases (42/54) were chronic. Evidence of concurrent biliary disease (46.2%) and biliary tract obstruction (42.6%) was common. Seventeen of 36 biliary and 11 of 25 liver cultures were positive for bacterial growth; Escherichia coli and Enterococcus spp. were most common. Median patient survival was 671 days (95% confidence interval [CI]: 114-1,426). On Cox regression, dogs that did not have a cholecystectomy performed had a 2.1 greater hazard for death (P = 0.037; 95% CI: 1.0-4.3) compared to cholecystectomized dogs. Dogs >13 years old had a 5.0 greater hazard for death (P = 0.001; 95% CI: 1.9-13.2) compared to younger dogs. CONCLUSIONS AND CLINICAL SIGNIFICANCE: Chronic NC or cholangiohepatitis was most common. Cholecystitis and biliary tract obstruction often occurred in conjunction with cholangitis. Cholecystectomized dogs had decreased risk of death; thus, cholecystectomy may improve patient outcome.
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