Evidence map›Paper›PMID 29131392›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2018

Virus detection in critically ill children with acute respiratory disease: a new profile in view of new technology.

Atsushi Kawaguchi, Angela Bates, Bonita E Lee, Steven Drews, Daniel Garros

Open access · bronzeAbstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Atsushi KawaguchiDepartment of Pediatrics, Pediatric Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.
Angela BatesDepartment of Pediatrics, Pediatric Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.
Bonita E LeeDepartment of Pediatrics, Pediatric Infectious Disease, University of Alberta, Edmonton, AB, Canada.
Steven DrewsProvincial Laboratory for Public Health, Alberta Health Services, Edmonton, AB, Canada.
Daniel GarrosDepartment of Pediatrics, Pediatric Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.
University of Alberta · CAAlberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe the epidemiology of critically ill children admitted to a paediatric intensive care unit (PICU) with acute respiratory disease. The association with intubation was analysed for the three most prevalent viruses and in those with and without viral co-infection.

methodsPatients admitted to the PICU (2004-2014) with acute respiratory disease were included. Analyses were performed utilising each respiratory viral infection or multiple viral infections as an exposure.

resultsThere were 1766 admissions with acute respiratory disease of which 1372 had respiratory virus testing and 748 had one or more viruses detected. The risk of intubation before or during the PICU stay was higher if parainfluenza virus was detected compared to respiratory syncytial virus (RSV) (OR: 2.20; 95% CI: 1.06-4.56). Sixty-three admissions had two or more viruses detected, and the combination of RSV and Rhinovirus/enterovirus was the most common. No significant difference was observed in the risk of intubation between patients with multiple and single viral infections.

conclusionHigher risk of intubation was found in patients with parainfluenza as compared to RSV. The risk of intubation comparing parainfluenza virus to other viruses and for patients with multiple versus single virus needs to be further studied.

Indexed as

Intensive Care Units, PediatricAcute DiseaseCanadaChildChild, PreschoolCohort StudiesCritical IllnessFemaleFollow-Up StudiesHospitalizationHumansInfantLength of StayMaleParamyxoviridae InfectionsRespiratory Syncytial Virus, HumanCritical careIntubationRespiratory diseaseViral infection

Identifiers

PMID29131392
PMCPMC7159542
OpenAlexW2768438595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.