ArticleBone marrow transplantation2018
Treatment intensity and symptom burden in hospitalized adolescent and young adult hematopoietic cell transplant recipients at the end of life.
Article in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Palliative care involvement and intensity of end-of-life care among adolescents and young adults with cancer: a population-based study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Article
- Palliative care for adolescents and young adults with advanced illness: A scoping review.Palliative medicine · 2023Article
- Patient, Family, and Clinician Perspectives on Location of Death for Adolescents and Young Adults With Cancer.JCO oncology practice · 2022Article
- Quality of Life in Adolescents and Young Adults: The Role of Symptom Burden.Journal of pain and symptom management · 2022Observational
- A Support System for Adolescent and Young Adult Patients with Cancer at a Comprehensive Cancer Center.JMA journal · 2022Review
- Compassionate de-escalation of life-sustaining treatments in pediatric oncology: An opportunity for palliative care and intensive care collaboration.Frontiers in oncology · 2022Article
- Article
- Specialized Pediatric Palliative Care Services in Pediatric Hematopoietic Stem Cell Transplant Centers.Children (Basel, Switzerland) · 2021Article
- Thoughts from the threshold: patient and family hopes, fears, values, and goals at the onset of pediatric hematopoietic cell transplantation.Bone marrow transplantation · 2020Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Adolescent and young adult (AYA) oncology patients experience many physical and psychological symptoms at the end of life (EOL); however, data on these experiences for AYA patients who have undergone hematopoietic cell transplantation (HCT) remains sparse. We sought to investigate the characteristics of AYA patients aged 15-25 years who received allogeneic HCT and subsequently died while inpatient at our institution between the years 2008 and 2014. A standardized data extraction tool was used to collect information about patient demographics, treatment and symptoms. We found that during this time frame, 34 AYA patients had received HCT and died while inpatient at our institution, 23 (68%) of whom died because of treatment-related complications. Compared with non-HCT AYA oncology patients (n=35), patients who received HCT (n=34) were more likely to have died in the intensive care unit (71% vs 23%, P<0 .0001) and to have received mechanical ventilation (68% vs 17%, P<0.0001) or hemodialysis (53% vs 0%, P<0.0001) in the last 30 days of life. These findings demonstrate that AYA patients who receive allogeneic HCT receive intensive EOL treatment, suggesting that these patients may benefit from early integration of expert interdisciplinary services to prospectively assess and manage distressing symptoms.
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