Trial reportMedical principles and practice : international journal of the Kuwait University, Health Science Centre2017
Low Tidal Volume Positive End-Expiratory Pressure versus High Tidal Volume Zero-Positive End-Expiratory Pressure and Postoperative Pulmonary Functions in Robot-Assisted Laparoscopic Radical Prostatectomy.
Trial report in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04546932 (Lung-protective Mechanical Ventilation for Patients Undergoing Abdominal Laparoscopic Surgeries), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Lung-protective Mechanical Ventilation for Patients Undergoing Abdominal Laparoscopic Surgeries: A Randomized Controlled Trial
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Intra-operative ventilation strategies and their impact on clinical outcomes: a systematic review and network meta-analysis of randomised trials.Anaesthesia · 2025Pooled it
- Intraoperative respiratory and hemodynamic strategies for reducing nausea, vomiting, and pain after surgery: Systematic review and meta-analysis.Acta anaesthesiologica Scandinavica · 2022Pooled it
- Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in adults without acute lung injury.The Cochrane database of systematic reviews · 2018Pooled it
- Individualised Positive End-Expiratory Pressure During Robotic-Assisted Radical Prostatectomy Guided by Intratidal Compliance-Volume Curve Analysis.Acta anaesthesiologica Scandinavica · 2025Trial
- Effect of pressure-controlled ventilation-volume guaranteed mode combined with individualized positive end-expiratory pressure on respiratory mechanics, oxygenation and lung injury in patients undergoing laparoscopic surgery in Trendelenburg position.Journal of clinical monitoring and computing · 2022Trial
- Protective mechanical ventilation with optimal PEEP during RARP improves oxygenation and pulmonary indexes.Trials · 2021Trial
- Lung-protective mechanical ventilation for patients undergoing abdominal laparoscopic surgeries: a randomized controlled trial.BMC anesthesiology · 2021Trial
- Effects of an Alveolar Recruitment Maneuver During Lung Protective Ventilation on Postoperative Pulmonary Complications in Elderly Patients Undergoing Laparoscopy.Clinical interventions in aging · 2020Trial
- Effect of intraoperative lung-protective mechanical ventilation on pulmonary oxygenation function and postoperative pulmonary complications after laparoscopic radical gastrectomy.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Trial
- A structured narrative review of clinical and experimental studies of the use of different positive end-expiratory pressure levels during thoracic surgery.The clinical respiratory journal · 2022Review
- Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy on postoperative hepatic and renal function.Gland surgery · 2020Article
- Individualized lung protective ventilation vs. conventional ventilation during general anesthesia in laparoscopic total hysterectomy.Experimental and therapeutic medicine · 2020Article
- Article
- Exploring the intraoperative lung protective ventilation of different positive end-expiratory pressure levels during abdominal laparoscopic surgery with Trendelenburg position.Annals of translational medicine · 2019Article
- The effect of intraoperative lung protective ventilation vs conventional ventilation, on postoperative pulmonary complications after cardiopulmonary bypass.Journal of cardiovascular and thoracic research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim was to compare the effects of low tidal volume (VT) and moderate positive end-expiratory pressure (PEEP) with high VT and zero end-expiratory pressure (ZEEP) on postoperative pulmonary functions and oxygenation in patients undergoing robot-assisted laparoscopic radical prostatectomy. SUBJECTS AND
methodsForty-four patients were randomized into low VT-PEEP and high VT-ZEEP groups. The patients were ventilated with a VT of 6 mL/kg and 8 cm H2O PEEP in the low VT-PEEP group and a VT of 10 mL/kg and 0 cm H2O PEEP in the high VT-ZEEP group. Preoperative and postoperative spirometric measurements were done and chest X-rays were evaluated using the radiological atelectasis score (RAS). p < 0.05 was considered statistically significant.
resultsThe intraoperative and postoperative arterial partial pressure of oxygen and arterial oxygen saturation values were significantly higher in the low VT-PEEP group than in the high VT-ZEEP group. At all times, the arterial-to-alveolar oxygenation gradients were significantly lower in the low VT-PEEP group than in the high VT-ZEEP group. Preoperative RAS were similar in both groups, but the postoperative RAS was significantly lower in the low VT-PEEP group (p < 0.001). Forced vital capacity, forced expiratory volume in 1 s, and peak expiratory flow rate recorded postoperatively were significantly lower in the high VT-ZEEP group (p < 0.001).
conclusionsPostoperative pulmonary functions were less impaired in patients ventilated with a VT of 6 mL/kg and 8 cm H2O PEEP than in patients ventilated with a VT of 10 mL/kg and ZEEP.
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