Evidence map›Paper›PMID 29130830›Full record

ArticleViral immunology2017

Enhanced CD103 Expression and Reduced Frequencies of Virus-Specific CD8

Sherri L Surman, Bart G Jones, David L Woodland, Julia L Hurwitz

Registry-linked trialAbstract read
In one paragraph

Article in Viral immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04519034 (Retrospective Pilot Study of Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04519034 completednot on this mapstarted 2020, after this paper: background citation

Retrospective Pilot Study of Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection

TypeobservationalSponsorGuy's and St Thomas' NHS Foundation TrustRan2020 to 2021Enrolled27,628ConditionsCovid19Armsno intervention
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Influenza in High-Risk Hosts-Lessons Learned from Animal Models.Cold Spring Harbor perspectives in medicine · 2020
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sherri L Surman1 Department of Infectious Diseases, St. Jude Children's Research Hospital , Memphis, Tennessee.
Bart G Jones1 Department of Infectious Diseases, St. Jude Children's Research Hospital , Memphis, Tennessee.
David L Woodland2 Trudeau Institute , Saranac Lake, New York.
Julia L Hurwitz1 Department of Infectious Diseases, St. Jude Children's Research Hospital , Memphis, Tennessee.
St. Jude Children's Research Hospital · USTrudeau Institute · USUniversity of Tennessee Health Science Center · US

Funding

Influence of maternal antibodies on a Sendai virus-vectored RSV vaccineR01AI088729 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI DEVINCENZO, JOHN P., HURWITZ, JULIA L · 2010 to 2014
$3.0M
NIAID NIH HHS R01 AI088729
6 · The paper itself

Abstract

Previous research has evaluated antibody responses toward an influenza virus vaccine in the context of deficiencies for vitamins A and D (VAD+VDD). Results showed that antibodies and antibody-forming cells in the respiratory tract were reduced in VAD+VDD mice. However, effectors were recovered when oral supplements of vitamins A + D were delivered at the time of vaccination. Here we address the question of how vaccine-induced CD8

Indexed as

AnimalsAntigens, CDCD8-Positive T-LymphocytesDietary SupplementsDisease Models, AnimalFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesIntegrin alpha ChainsLymphocytesMiceMice, Inbred C57BLRespiratory SystemTreatment Outcomealpha E integrinsAntigens, CDInfluenza VaccinesIntegrin alpha ChainsVitaminsbronchoalveolar lavageinfluenza virusvaccine-induced T cellsvitamin deficiencyvitamins A and D

Identifiers

PMID29130830
PMCPMC5709699
OpenAlexW2769721566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.