Evidence map›Paper›PMID 29130162›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

"Hot Stuff": The Many Uses of a Radiolabel Assay in Detecting Acyl-Homoserine Lactone Quorum-Sensing Signals.

Amy L Schaefer, Caroline S Harwood, E Peter Greenberg

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. AmBio · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. ThemBio · 2018
    Article
  10. An aryl-homoserine lactone quorum-sensing signal produced by a dimorphic prosthecate bacterium.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amy L SchaeferDepartment of Microbiology, University of Washington, Seattle, WA, USA. amyschae@uw.edu.
Caroline S HarwoodDepartment of Microbiology, University of Washington, Seattle, WA, USA.
E Peter GreenbergDepartment of Microbiology, University of Washington, Seattle, WA, USA. epgreen@uw.edu.
University of Washington · USSeattle University · US

Funding

QUORUM SENSING IN PSEUDOMONAS AERUGINOSAR01GM059026 · NIGMS · UNIVERSITY OF WASHINGTON · PI GREENBERG, EVERETT P · 1999 to 2019
$6.5M
NIGMS NIH HHS R01 GM059026
6 · The paper itself

Abstract

Many Proteobacteria synthesize acyl-homoserine lactone (AHL) molecules for use as signals in cell density-dependent gene regulation known as quorum sensing (QS) and response. AHL detection protocols are essential to QS researchers and several techniques are available, including a

Indexed as

Quorum SensingSignal TransductionAcyl-ButyrolactonesBacteriaChromatography, High Pressure LiquidIsotope LabelingLigasesRadioisotopesSubstrate SpecificityAcyl-ButyrolactonesLigasesN-acylhomoserine lactone synthaseRadioisotopes14C-carboxy-methionineAcyl-homoserine lactoneAcyl-HSLAHLLuxIQSQuorum sensing

Identifiers

PMID29130162
PMCPMC5805386
OpenAlexW2767608947

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.