Evidence map›Paper›PMID 29130078›Full record

ArticleJacobs journal of diabetes and endocrinology2016

Hepatic Adaptations to a High Fat Diet in the MRL Mouse Strain are Associated with an Inefficient Oxidative Phosphorylation System.

Ahlke Heydemann, Magdalis González-Vega, Tirsit K Berhanu, Aaron J Mull, Ragav Sharma, Jenan Holley-Cuthrell

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Jacobs journal of diabetes and endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ahlke HeydemannDepartment of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Magdalis González-VegaDepartment of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Tirsit K BerhanuDepartment of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Aaron J MullDepartment of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Ragav SharmaDepartment of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Jenan Holley-CuthrellDepartment of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
University of Illinois Chicago · US

Funding

Mechanisms and therapies for respiratory muscle failureR01HL102322 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HEYDEMANN, AHLKE · 2011 to 2014
$1.5M
PAK1 Activation Reduces Muscular Dystrophy-Mediated FibrosisR21AR069196 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GARCIA-MARTINEZ, JESUS, HEYDEMANN, AHLKE · 2016 to 2017
$387k
NHLBI NIH HHS R01 HL102322NIAMS NIH HHS R21 AR069196
6 · The paper itself

Abstract

The MRL mice are resistant to a 12-week high fat diet (HFD) feeding protocol, with the proximal cause being an increased basal pAMPK

Indexed as

AMPKglycogenhigh fat dietliverMRL miceoxidative phosphorylationsteatosis

Identifiers

PMID29130078
PMCPMC5681357
OpenAlexW2991138269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.