ArticleJournal of ophthalmology2017
Changes in Retinal and Choroidal Vascular Blood Flow after Oral Sildenafil: An Optical Coherence Tomography Angiography Study.
Article in Journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- The choroid as a vascular sensor in pulmonary hypertension: an oculomic mini review.Frontiers in cardiovascular medicine · 2026Review
- Long-term follow-up of retinal morphology and physiology after 2000 mg sildenafil overdose as a means of attempted suicide: a case report.BMC ophthalmology · 2022Article
- Unilateral acute anterior uveitis with macular edema following the use of sildenafil citrate in a patient with HLA-B27 positivity.American journal of ophthalmology case reports · 2021Article
- Visual Side Effects Linked to Sildenafil Consumption: An Update.Biomedicines · 2021Review
- [Chorioretinal folds of interesting etiology].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Article
- Optical coherence tomography angiography-derived flow density: a review of the influencing factors.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Review
- Optical Coherence Tomography Angiography Findings in Deficiency Optic Neuropathy.Neuro-ophthalmology (Aeolus Press) · 2019Article
- Retinal and choroidal vascular changes in coronary heart disease: an optical coherence tomography angiography study.Biomedical optics express · 2019Article
- Quetiapine associated Central Serous Chorioretinopathy: Implicit role of serotonin and dopamine pathways.Indian journal of ophthalmology · 2019Article
- Investigation of the effects of temporomandibular joint arthrocentesis on blood volume of the retinal structures.Journal of dental anesthesia and pain medicine · 2019Article
- Spontaneous resolution of myopic retinoschisis.AME case reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe changes in the retina and choroidal flow by optical coherence tomography angiography (OCT-A) after a single dose of oral sildenafil.
methodA case-control study. Patients in the study group received 50 mg of oral sildenafil. Patients in the control group received a sham pill. Retinal and choroidal images were obtained at baseline (before pill ingestion) and 1 hour after ingestion. Central macular and choroidal thickness, choroidal and outer retina flow, and the retinal and choroidal vascular density were compared using a Mann-Whitney
resultsTwenty eyes were enrolled into the study group and 10 eyes in the control group. There was a significant difference in central choroidal thickness and outer retina blood flow between groups after 1 hour of sildenafil ingestion (
conclusionsA single dose of oral sildenafil increases choroidal thickness, probably due to sildenafil-induced vasodilation.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.