Evidence map›Paper›PMID 29129973›Full record

ArticleGastroenterology research and practice2017

Are the Symptoms of an NSAID-Induced Ulcer Truly Milder Than Those of an Ordinary Ulcer?

Toshihiko Tomita, Sumire Mori, Katsuyuki Tozawa, Eitatsu Arai, Nobuo Tano, Hideo Oka, Yongmin Kim, Takashi Abe, Yoshio Ohda, Tadayuki Oshima and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Toshihiko TomitaDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.ORCID 0000-0003-1283-9009
Sumire MoriDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Katsuyuki TozawaDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Eitatsu AraiDepartment of Internal Medicine, Nishinomiya Kyoritsu Neurosurgical Hospital, Hyogo, Japan.
Nobuo TanoDepartment of Internal Medicine, Kyoritsu Hospital, Hyogo, Japan.
Hideo OkaDepartment of Internal Medicine, Amagasaki Central Hospital, Hyogo, Japan.
Yongmin KimDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Takashi AbeDivision of Gastroenterology, Takarazuka Municipal Hospital, Hyogo, Japan.
Yoshio OhdaDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Tadayuki OshimaDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.ORCID 0000-0001-6949-932X
Hirokazu FukuiDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Jiro WatariDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Hiroto MiwaDivision of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.ORCID 0000-0001-9844-642X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe percentage of patients with nonsteroidal anti-inflammatory drugs (NSAIDs) and low-dose aspirin- (LDA-) induced ulcers who complain of gastrointestinal symptoms has generally been considered to be low. The aim of this study was to examine and compare the symptoms and quality of life (QOL) at peptic ulcer onset.

methodsThis study involved 200 patients who were confirmed by endoscopy to be in the acute stage of gastroduodenal ulcer (A1-H1). Patients completed a self-administered questionnaire (Global Overall Symptom score and SF-8) at ulcer onset, and data were compared between NSAIDs/LDA ulcers and non-NSAIDs/LDA ulcers.

resultsThe upper gastrointestinal symptoms score was significantly lower for patients using LDA only (20.5 ± 9.4 in the nonusing group, 19.6 ± 8.6 in the NSAIDs-only group, 16.7 ± 11.6 in the LDA-only group, and 18.5 ± 7.2 in the NSAIDs/LDA group,

conclusionThe severity of upper abdominal symptoms at peptic ulcer onset was similar between NSAID users and nonusers.

Identifiers

PMID29129973
PMCPMC5654275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.