Evidence map›Paper›PMID 29129946›Full record

ArticleProgress in materials science2017

Application of Materials as Medical Devices with Localized Drug Delivery Capabilities for Enhanced Wound Repair.

Esther J Lee, Beom Kang Huh, Se Na Kim, Jae Yeon Lee, Chun Gwon Park, Antonios G Mikos, Young Bin Choy

Abstract read
In one paragraph

Article in Progress in materials science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Advances in Medical Devices for Augmented Acupuncture Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Recent advances in nanoengineering cellulose for cargo delivery.Journal of controlled release : official journal of the Controlled Release Society · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esther J LeeDepartment of Bioengineering, Rice University, MS 142, P.O. Box 1892, Houston, Texas, 77251-1892, USA.
Beom Kang HuhInterdisciplinary Program for Bioengineering, Seoul National University College of Engineering, Seoul, Republic of Korea.
Se Na KimInterdisciplinary Program for Bioengineering, Seoul National University College of Engineering, Seoul, Republic of Korea.
Jae Yeon LeeInterdisciplinary Program for Bioengineering, Seoul National University College of Engineering, Seoul, Republic of Korea.
Chun Gwon ParkInstitute of Medical & Biological Engineering, Medical Research Center, Seoul National University, Seoul, Republic of Korea.
Antonios G MikosDepartment of Bioengineering, Rice University, MS 142, P.O. Box 1892, Houston, Texas, 77251-1892, USA.
Young Bin ChoyInterdisciplinary Program for Bioengineering, Seoul National University College of Engineering, Seoul, Republic of Korea.

Funding

In Situ Hardening Cell-Laden Constructs for Osteochondral Tissue EngineeringR01AR068073 · NIAMS · RICE UNIVERSITY · PI MIKOS, ANTONIOS G. · 2015 to 2019
$1.7M
An Optogenetic Approach to Bone Tissue EngineeringR21AR067527 · NIAMS · RICE UNIVERSITY · PI MIKOS, ANTONIOS G., TABOR, JEFFREY JAY · 2015 to 2016
$356k
NIAMS NIH HHS R01 AR068073NIAMS NIH HHS R21 AR067527
6 · The paper itself

Abstract

The plentiful assortment of natural and synthetic materials can be leveraged to accommodate diverse wound types, as well as different stages of the healing process. An ideal material is envisioned to promote tissue repair with minimal inconvenience for patients. Traditional materials employed in the clinical setting often invoke secondary complications, such as infection, pain, foreign body reaction, and chronic inflammation. This review surveys the repertoire of surgical sutures, wound dressings, surgical glues, orthopedic fixation devices and bone fillers with drug eluting capabilities. It highlights the various techniques developed to effectively incorporate drugs into the selected material or blend of materials for both soft and hard tissue repair. The mechanical and chemical attributes of the resultant materials are also discussed, along with their biological outcomes

Indexed as

Drug deliveryMaterialMedical deviceWound repair

Identifiers

PMID29129946
PMCPMC5679315

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.