Evidence map›Paper›PMID 29129876›Full record

ReviewMicrobes and environments2017

Microbial Ecology along the Gastrointestinal Tract.

Ethan T Hillman, Hang Lu, Tianming Yao, Cindy H Nakatsu

Abstract readReview
In one paragraph

Review in Microbes and environments, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 296 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
296citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

296 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Fecal Microbiota Transplantation BeyondJournal of Korean medical science · 2026
    Review
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236 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ethan T HillmanDepartment of Agricultural and Biological Engineering, Purdue University.
Hang LuDepartment of Animal Science, Purdue University.
Tianming YaoDepartment of Food Science, Purdue University.
Cindy H NakatsuDepartment of Agronomy, Purdue University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ecosystem of the human gastrointestinal (GI) tract traverses a number of environmental, chemical, and physical conditions because it runs from the oral cavity to the anus. These differences in conditions along with food or other ingested substrates affect the composition and density of the microbiota as well as their functional roles by selecting those that are the most suitable for that environment. Previous studies have mostly focused on Bacteria, with the number of studies conducted on Archaea, Eukarya, and Viruses being limited despite their important roles in this ecosystem. Furthermore, due to the challenges associated with collecting samples directly from the inside of humans, many studies are still exploratory, with a primary focus on the composition of microbiomes. Thus, mechanistic studies to investigate functions are conducted using animal models. However, differences in physiology and microbiomes need to be clarified in order to aid in the translation of animal model findings into the context of humans. This review will highlight Bacteria, Archaea, Fungi, and Viruses, discuss differences along the GI tract of healthy humans, and perform comparisons with three common animal models: rats, mice, and pigs.

Indexed as

AnimalsArchaeaBacteriaBiodiversityDietFoodFungiGastrointestinal MicrobiomeGastrointestinal TractHumansMiceModels, AnimalRatsSwineVirusesanimal modelsdiethuman gastrointestinal (GI) tractMicrobiomemycobiomevirome

Identifiers

PMID29129876
PMCPMC5745014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.