ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2018
Association of Perioperative Redox Balance on Long-Term Outcome in Patients Undergoing Lung Resection.
Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Contribution of oxidative stress in the mechanisms of postoperative complications and multiple organ dysfunction syndrome.Redox report : communications in free radical research · 2021Pooled it
- Association between oxidative stress index and lung cancer risk in idiopathic pulmonary fibrosis: an exploratory retrospective analysis.Translational lung cancer research · 2026Article
- Regional Anesthesia: A Narrative Review of Impact on Oxidative Stress Biomarkers.Journal of clinical medicine · 2025Review
- Exploring the role of antioxidants in sepsis-associated oxidative stress: a comprehensive review.Frontiers in cellular and infection microbiology · 2024Review
- Perioperative redox changes in patients undergoing hepato-pancreatico-biliary cancer surgery.Perioperative medicine (London, England) · 2023Article
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7 authors.
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Abstract
purposeWe examined whether redox balance during the perioperative period is associated with long-term survival of patients after undergoing lung resection.
methodsPatients who underwent surgery for lung cancer from January to June 2013 at our institution were investigated. Serum was collected during the operation, and on postoperative day (POD) 3 and 7, and the levels of derivatives of reactive oxygen metabolites (d-ROMs) and biologic antioxidant potential (BAP) were measured.
resultsIn all, 21 patients (69 ± 7 years old) were enrolled, of whom 9 underwent video-assisted thoracoscopic surgery. Comorbidities in the patients included chronic obstructive pulmonary disease in eight and idiopathic pulmonary fibrosis in five. d-ROM values on POD 3 and 7 were significantly increased as compared to those obtained during the operation (p <0.001), whereas BAP did not change after surgery. Patients with a value below a d-ROM cutoff value of 327 during the operation showed significantly superior 3-year overall survival as compared to those with a value above the cutoff (87.5% vs. 20.0%, p <0.001).
conclusionIn the present patients, surgical stress caused an increase in d-ROM during the postoperative course. The d-ROM value obtained during the operation was correlated with long-term survival following resection for lung cancer.
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