ArticleStem cell reports2017
Non-monotonic Changes in Progenitor Cell Behavior and Gene Expression during Aging of the Adult V-SVZ Neural Stem Cell Niche.
Article in Stem cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 43 citations in OpenAlex.
- Quiescence as an Active and Dynamic Regulator of Neural Stem Cells in Adult Olfactory Neurogenesis.The European journal of neuroscience · 2026Review
- The hippocampal subgranular zone neurogenic niche: a modular perspective on neural stem cell regulation.Frontiers in cellular neuroscience · 2026Review
- The subventricular zone structure, function and implications for neurological disease.Genes & diseases · 2025Review
- Developmental regulation of long-range neuroblast migration by Eph/ephrin signaling.Frontiers in neuroscience · 2025Article
- A Human Embryonic Stem Cell-derived Neural Stem Cell Senescence Model Triggered by Oxidative Stress.Current stem cell research & therapy · 2025Article
- A Kolmogorov metric embedding for live cell microscopy signaling patterns.Bioinformatics advances · 2025Article
- Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response.Frontiers in neuroscience · 2024Article
- Leveraging metabolic modeling and machine learning to uncover modulators of quiescence depth.PNAS nexus · 2024Article
- Dbx2, an Aging-Related Homeobox Gene, Inhibits the Proliferation of Adult Neural Progenitors.Stem cell reviews and reports · 2023Article
- Endogenous neural stem cells characterization using omics approaches: Current knowledge in health and disease.Frontiers in cellular neuroscience · 2023Review
- Article
- 4D imaging analysis of the aging mouse neural stem cell niche reveals a dramatic loss of progenitor cell dynamism regulated by the RHO-ROCK pathway.Stem cell reports · 2022Article
- Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging.Scientific reports · 2022Article
- Assessing the Role of Ependymal and Vascular Cells as Sources of Extracellular Cues Regulating the Mouse Ventricular-Subventricular Zone Neurogenic Niche.Frontiers in cell and developmental biology · 2022Review
- Article
- Enhanced NRF2 expression mitigates the decline in neural stem cell function during aging.Aging cell · 2021Article
- 3D Image Analysis of the Complete Ventricular-Subventricular Zone Stem Cell Niche Reveals Significant Vasculature Changes and Progenitor Deficits in Males Versus Females with Aging.Stem cell reports · 2021Article
- Manipulation of EGFR-Induced Signaling for the Recruitment of Quiescent Neural Stem Cells in the Adult Mouse Forebrain.Frontiers in neuroscience · 2021Article
- Vascular Senescence: A Potential Bridge Between Physiological Aging and Neurogenic Decline.Frontiers in neuroscience · 2021Review
- Syndecan-1 Stimulates Adult Neurogenesis in the Mouse Ventricular-Subventricular Zone after Injury.iScience · 2020Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Neural stem cell activity in the ventricular-subventricular zone (V-SVZ) decreases with aging, thought to occur by a unidirectional decline. However, by analyzing the V-SVZ transcriptome of male mice at 2, 6, 18, and 22 months, we found that most of the genes that change significantly over time show a reversal of trend, with a maximum or minimum expression at 18 months. In vivo, MASH1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.