ArticleCurrent biology : CB2017
Idiosyncratic Genome Degradation in a Bacterial Endosymbiont of Periodical Cicadas.
Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Convergent extreme reductive evolution in ancient planthopper symbioses.Nature communications · 2026Article
- Genome degradation results in nested symbiosis and endosymbiont replacement in cicadas.Nature communications · 2025Article
- From eggs to guts: Symbiotic association of Sodalis nezarae sp. nov. with the Southern green shield bug Nezara viridula.FEMS microbiology ecology · 2025Article
- Unveiling detoxifying symbiosis and dietary influence on the Southern green shield bug microbiota.FEMS microbiology ecology · 2024Article
- Article
- Facultatively intrabacterial localization of a planthopper endosymbiont as an adaptation to its vertical transmission.mSystems · 2024Article
- Segregation of endosymbionts in complex symbiotic system of cicadas providing novel insights into microbial symbioses and evolutionary dynamics of symbiotic organs in sap-feeding insects.Frontiers in zoology · 2024Article
- Retention of an Endosymbiont for the Production of a Single Molecule.Genome biology and evolution · 2024Article
- Diurnal transcriptional variation is reduced in a nitrogen-fixing diatom endosymbiont.The ISME journal · 2024Article
- Sensitive and error-tolerant annotation of protein-coding DNA with BATH.Bioinformatics advances · 2024Article
- Sensitive and error-tolerant annotation of protein-coding DNA with BATH.bioRxiv : the preprint server for biology · 2024Article
- No Transcriptional Compensation for Extreme Gene Dosage Imbalance in Fragmented Bacterial Endosymbionts of Cicadas.Genome biology and evolution · 2023Article
- A complex interplay of evolutionary forces continues to shape ancient co-occurring symbiont genomes.iScience · 2022Article
- Genetic innovations in animal-microbe symbioses.Nature reviews. Genetics · 2022Review
- Adaptation and genomic erosion in fragmented Pseudomonas aeruginosa populations in the sinuses of people with cystic fibrosis.Cell reports · 2021Article
- A new protein protects a symbiotic relationship.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Inhibition of a nutritional endosymbiont by glyphosate abolishes mutualistic benefit on cuticle synthesis in Oryzaephilus surinamensis.Communications biology · 2021Article
- Bacterial Communities in Bacteriomes, Ovaries and Testes of three Geographical Populations of a Sap-Feeding Insect, Platypleura kaempferi (Hemiptera: Cicadidae).Current microbiology · 2021Article
- Mutational Pressure Drives Differential Genome Conservation in Two Bacterial Endosymbionts of Sap-Feeding Insects.Genome biology and evolution · 2021Article
- Evolution from Free-Living Bacteria to Endosymbionts of Insects: Genomic Changes and the Importance of the Chaperonin GroEL.Results and problems in cell differentiation · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
When a free-living bacterium transitions to a host-beneficial endosymbiotic lifestyle, it almost invariably loses a large fraction of its genome [1, 2]. The resulting small genomes often become stable in size, structure, and coding capacity [3-5], as exemplified by Sulcia muelleri, a nutritional endosymbiont of cicadas. Sulcia's partner endosymbiont, Hodgkinia cicadicola, similarly remains co-linear in some cicadas diverged by millions of years [6, 7]. But in the long-lived periodical cicada Magicicada tredecim, the Hodgkinia genome has split into dozens of tiny, gene-sparse circles that sometimes reside in distinct Hodgkinia cells [8]. Previous data suggested that all other Magicicada species harbor complex Hodgkinia populations, but the timing, number of origins, and outcomes of the splitting process were unknown. Here, by sequencing Hodgkinia metagenomes from the remaining six Magicicada and two sister species, we show that each Magicicada species harbors Hodgkinia populations of at least 20 genomic circles. We find little synteny among the 256 Hodgkinia circles analyzed except between the most closely related cicada species. Gene phylogenies show multiple Hodgkinia lineages in the common ancestor of Magicicada and its closest known relatives but that most splitting has occurred within Magicicada and has given rise to highly variable Hodgkinia gene dosages among species. These data show that Hodgkinia genome degradation has proceeded down different paths in different Magicicada species and support a model of genomic degradation that is stochastic in outcome and nonadaptive for the host. These patterns mirror the genomic instability seen in some mitochondria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.