ArticleJournal of biomedical optics2017
Line-scanning confocal microendoscope for nuclear morphometry imaging.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Deployment and assessment of a deep learning model for real-time detection of anal precancer with high frame rate high-resolution microendoscopy.Scientific reports · 2023Article
- Scanning darkfield high-resolution microendoscope for label-free microvascular imaging.Biomedical optics express · 2023Article
- Flexible-type ultrathin holographic endoscope for microscopic imaging of unstained biological tissues.Nature communications · 2022Article
- Low-cost, chromatic confocal endomicroscope for cellular imagingBiomedical optics express · 2021Article
- In vivo imaging of cervical precancer using a low-cost and easy-to-use confocal microendoscope.Biomedical optics express · 2020Article
- Advances in technologies for cervical cancer detection in low-resource settings.Expert review of molecular diagnostics · 2019Review
- Improving nuclear morphometry imaging with real-time and low-cost line-scanning confocal microendoscope.Optics letters · 2019Article
- Fast confocal fluorescence imaging in freely behaving mice.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Fiber-optic endomicroscopy is a minimally invasive method to image cellular morphology in vivo. Using a coherent fiber bundle as an image relay, it allows additional imaging optics to be placed at the distal end of the fiber outside the body. In this research, we use this approach to demonstrate a compact, low-cost line-scanning confocal fluorescence microendoscope that can be constructed for <$5000. Confocal imaging is enabled without the need for mechanical scanning by synchronizing a digital light projector with the rolling shutter of a CMOS camera. Its axial performance is characterized in comparison with a nonscanned high-resolution microendoscope. We validate the optical sectioning capability of the microendoscope by imaging a two-dimensional phantom and ex vivo mouse esophageal and colon tissues. Results show that optical sectioning using this approach improves visualization of nuclear morphometry and suggest that this low-cost line-scanning microendoscope can be used to evaluate various pathological conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.