Evidence map›Paper›PMID 29128917›Full record

ArticleJournal of bioenergetics and biomembranes2017

Heterologous expression of mitochondrial nicotinamide adenine dinucleotide transporter (Ndt1) from Aspergillus fumigatus rescues impaired growth in Δndt1Δndt2 Saccharomyces cerevisiae strain.

Laís de Lourdes de Lima Balico, Emerson de Souza Santos, Silveli Suzuki-Hatano, Lucas Oliveira Sousa, Ana Elisa Caleiro Seixas Azzolini, Yara Maria Lucisano-Valim, Taisa Magnani Dinamarco, Vinicius Kannen, Sérgio Akira Uyemura

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In one paragraph

Article in Journal of bioenergetics and biomembranes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Laís de Lourdes de Lima BalicoUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Emerson de Souza SantosUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Silveli Suzuki-HatanoUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Lucas Oliveira SousaUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Ana Elisa Caleiro Seixas AzzoliniUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Yara Maria Lucisano-ValimUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Taisa Magnani DinamarcoUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Vinicius KannenUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Sérgio Akira UyemuraUniversidade de Sao Paulo, Ribeirão Preto, São Paulo, Brazil. suyemura@fcfrp.usp.br.
Universidade de São Paulo · BRUniversidade de Ribeirão Preto · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304842/2014-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/15861-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/20031-8
6 · The paper itself

Abstract

Our understanding of nicotinamide adenine dinucleotide mitochondrial transporter 1 (Ndt1A) in Aspergillus fumigatus remains poor. Thus, we investigated whether Ndt1A could alter fungi survival. To this end, we engineered the expression of an Ndt1A-encoding region in a Δndt1Δndt2 yeast strain. The resulting cloned Ndt1A protein promoted the mitochondrial uptake of nicotinamide adenine dinucleotide (NAD

Indexed as

Aspergillus fumigatusGene DeletionHeterograftsMembrane Potential, MitochondrialMitochondriaMitochondrial ProteinsNADNucleotide Transport ProteinsOrganic Cation Transport ProteinsOxidative StressSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsMitochondrial ProteinsNADNdt1 protein, S cerevisiaeNucleotide Transport ProteinsOrganic Cation Transport ProteinsSaccharomyces cerevisiae ProteinsAspergillus fumigatusCell growthGene expressionMitochondrial nicotinamide adenine dinucleotide transporterProtein synthesisTransformation

Identifiers

PMID29128917
OpenAlexW2767769639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.