Evidence map›Paper›PMID 29128916›Full record

ReviewCurrent diabetes reports2017

Cardiometabolic Risk in PCOS: More than a Reproductive Disorder.

Laura C Torchen

Open access · greenAbstract readReview
In one paragraph

Review in Current diabetes reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. The Menstrual Cycle and Sleep.Sleep medicine clinics · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. The consumption of micronutrients in relation to calorie intake and risk of insulin resistance.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Postmenopausal Hyperandrogenism: Evaluation and Treatment Strategies.Endocrinology and metabolism clinics of North America · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Laura C TorchenDivision of Endocrinology, Ann & Robert H Lurie Children's Hospital of Chicago, 225 E Chicago Ave, Box 54, Chicago, IL, 60611, USA. LTorchen@luriechildrens.org.
Lurie Children's Hospital · US

Funding

A Prospective Study of Biochemical and Genetic Predictors of PCOS in High Risk Early Postmenarchal GirlsK23HD090274 · NICHD · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI TORCHEN, LAURA C · 2017 to 2019
$489k
NICHD NIH HHS K23 HD090274
6 · The paper itself

Abstract

purpose of reviewPolycystic ovary syndrome (PCOS) is diagnosed by its characteristic reproductive features. However, PCOS is also associated with metabolic abnormalities, including insulin resistance and β-cell dysfunction. The severity of these abnormalities varies according to the reproductive phenotype, with the so-called NIH or classic phenotype conferring the greatest metabolic risk. The increased risk for type 2 diabetes (T2D) is well established among affected women with the NIH phenotype, but whether PCOS also confers an increased risk for cardiovascular events remains unknown. RECENT

findingsRecent studies in daughters of affected women have found evidence for pancreatic β-cell dysfunction prior to menarche. Further, genetic analyses have provided evidence that metabolic abnormalities such as obesity and insulin resistance contribute to the pathogenesis of PCOS. PCOS increases the risk for T2D. However, the risk for cardiovascular disease has not been quantified, and prospective, longitudinal studies are still critically needed.

Indexed as

Cardiovascular DiseasesFemaleHumansInsulin ResistanceMetabolic SyndromePhenotypePolycystic Ovary SyndromeRisk FactorsCardiovascular diseaseInsulin resistanceObesityPolycystic ovary syndromeType 2 diabetes

Identifiers

PMID29128916
PMCPMC5823507
OpenAlexW2767757583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.