ReviewCurrent opinion in pharmacology2017
Pharmacological management of gastroesophageal reflux disease in infants: current opinions.
Review in Current opinion in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- GERD management in neonatal ICU infants: study protocol for a randomized controlled trial comparing maturation, added rice starch formula and proton pump inhibitors.BMC pediatrics · 2026Trial
- Impact of Feeding Strategies With Acid Suppression on Esophageal Reflexes in Human Neonates With Gastroesophageal Reflux Disease: A Single-Blinded Randomized Clinical Trial.Clinical and translational gastroenterology · 2020Trial
- Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial.European journal of drug metabolism and pharmacokinetics · 2020Trial
- Medical treatment of gastroesophageal reflux in the neonatal intensive care unit: current practice.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Improving growth in preterm infants through nutrition: a practical overview.Frontiers in nutrition · 2024Review
- Nurses' knowledge and practice regarding mixing medications with food: a multicenter cross-sectional study from a developing country.Journal of health, population, and nutrition · 2023Article
- Iron Deficiency Anemia in Pediatric Gastroesophageal Reflux Disease.Diagnostics (Basel, Switzerland) · 2022Article
- Impact of esophageal mucosal permeability markers on provocation-induced esophageal reflexes in high-risk infants.Physiological reports · 2022Article
- Unsolved problems in CDH follow-up.Frontiers in pediatrics · 2022Article
- Effects of upper airway obstruction or hypoxia on gastroesophageal reflux in newborn lambs.Pediatric research · 2021Article
- Cross-sectional study of drug utilisation in a Chinese neonatal unit.The Journal of international medical research · 2020Article
- The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink.International journal of pediatrics & adolescent medicine · 2020Article
- Gastroesophageal Reflux Disease in the Neonatal Intensive Care Unit Infant: Who Needs to Be Treated and What Approach Is Beneficial?Pediatric clinics of North America · 2019Review
- Gastroesophageal reflux in children: an updated review.Drugs in context · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Gastroesophageal reflux disease (GERD) constitutes a troublesome symptom complex resulting from retrograde passage of gastric contents into the esophagus or extra-esophageal regions. Premature-born, high-risk infants and those with neuro-aero-digestive pathologies are at increased risk. Critical review over the last 3 years was conducted, and current opinions on pharmacological targets include agents aimed at prevention of transient lower esophageal sphincter relaxation, modification of the physico-chemical composition of gastric contents, modification of gut motility, or altering sensory thresholds to ameliorate the troublesome symptoms. As data from well-designed studies is limited in the infant population, information from adult studies has been cited where potential application may be helpful.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.