Evidence map›Paper›PMID 29128412›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2018

Association Between Gestational Diabetes and Incident Maternal CKD: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

Elizabeth W Dehmer, Milind A Phadnis, Erica P Gunderson, Cora E Lewis, Kirsten Bibbins-Domingo, Stephanie M Engel, Michele Jonsson Funk, Holly Kramer, Abhijit V Kshirsagar, Gerardo Heiss

Open access · greenAbstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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  19. Nut Consumption and Renal Function Among Women With a History of Gestational Diabetes.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Elizabeth W DehmerDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address: weavereg@med.unc.edu.
Milind A PhadnisDepartment of Biostatistics, University of Kansas School of Medicine, Kansas City, KS.
Erica P GundersonDivision of Research, Kaiser Permanente Northern California, Oakland, CA.
Cora E LewisDivision of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Kirsten Bibbins-DomingoDepartment of Medicine, University of California San Francisco, San Francisco, CA; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.
Stephanie M EngelDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Michele Jonsson FunkDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Holly KramerDivision of Nephrology and Hypertension, Department of Public Health Sciences and Medicine, Loyola Medical Center, Maywood, IL.
Abhijit V KshirsagarUNC Kidney Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Gerardo HeissDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
University of North Carolina at Chapel Hill · USKaiser Permanente · USLoyola University Medical Center · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of Kansas · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Lactation and Incidence of Diabetes Mellitus in CARDIA WomenR01DK090047 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GUNDERSON, ERICA PAULINE · 2011 to 2014
$2.7M
Pregnancy-Related Risk Factors and Glucose Intolerance in Women during MidlifeR01DK106201 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GUNDERSON, ERICA PAULINE · 2015 to 2018
$2.7M
Hypertension Management in Minority and Low-income PopulationsK24DK103992 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2014 to 2018
$917k
Pregnancy and Risk Factors for CVD and Type 2 DiabetesK01DK059944 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GUNDERSON, ERICA PAULINE · 2002 to 2006
$640k
NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029CNIDDK NIH HHS K01 DK059944NIDDK NIH HHS K24 DK103992NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK090047NIDDK NIH HHS R01 DK106201
6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) is associated with increased risk for diabetes mellitus, metabolic syndrome, and cardiovascular disease. We evaluated whether GDM is associated with incident chronic kidney disease (CKD), controlling for prepregnancy risk factors for both conditions. STUDY

designProspective cohort. SETTING &

participantsOf 2,747 women (aged 18-30 years) enrolled in the Coronary Artery Risk Development in Young Adults (CARDIA) Study in 1985 to 86, we studied 820 who were nulliparous at enrollment, delivered at least 1 pregnancy longer than 20 weeks' gestation, and had kidney function measurements during 25 years of follow-up. PREDICTOR: GDM was self-reported by women for each pregnancy. OUTCOMES: CKD was defined as the development of estimated glomerular filtration rate (eGFR)<60mL/min/1.73m MEASUREMENTS: HRs for developing CKD were estimated for women who developed GDM versus women without GDM using complementary log-log models, adjusting for prepregnancy age, systolic blood pressure, dyslipidemia, body mass index, smoking, education, eGFR, fasting glucose concentration, physical activity level (all measured at the CARDIA examination before the first pregnancy), race, and family history of diabetes. We explored for an interaction between race and GDM.

resultsDuring a mean follow-up of 20.8 years, 105 of 820 (12.8%) women developed CKD, predominantly increased urine albumin excretion (98 albuminuria only, 4 decreased eGFR only, and 3 both). There was evidence of a GDM-race interaction on CKD risk (P=0.06). Among black women, the adjusted HR for CKD was 1.96 (95% CI, 1.04-3.67) in GDM compared with those without GDM. Among white women, the HR was 0.65 (95% CI, 0.23-1.83). LIMITATIONS: Albuminuria was assessed by single untimed measurements of urine albumin and creatinine.

conclusionsGDM is associated with the subsequent development of albuminuria among black women in CARDIA.

Indexed as

AlbuminuriaCoronary Artery DiseaseDiabetes, GestationalRenal Insufficiency, ChronicAdultBlack or African AmericanBody Mass IndexCohort StudiesCreatinineFemaleHumansIncidenceKidney Function TestsPregnancyProspective StudiesRisk FactorsCreatinineAfrican Americanalbuminuriachronic kidney disease (CKD)CKD risk factordiabetes mellitusGestational diabetes mellitus (GDM)incident CKDpregnancyrace/ethnicity

Identifiers

PMID29128412
PMCPMC5742081
OpenAlexW2767518333

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.