ReviewPreventive medicine2018
Adding folic acid to corn Masa flour: Partnering to improve pregnancy outcomes and reduce health disparities.
Review in Preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Association between life's essential 8 and epilepsy: A cross-sectional study (NHANES 2013-2018).Medicine · 2026Article
- Release Dynamics of Folic Acid from Peptidomimetic Polyesters: A Multi-Scale Investigation from Bulk Properties to Molecular Interactions.Biomacromolecules · 2026Article
- Trends and Prevalence of Modifiable Risk Factors for Birth Defects Among U.S. Women of Reproductive Age: National Health and Nutrition Examination Survey 2007 to March 2020.American journal of preventive medicine · 2025Article
- The Neural Tube CURE: Engaging undergraduate students in a relevant developmental biology research course.Developmental biology · 2025Review
- Biological, dietetic and pharmacological properties of vitamin BNPJ science of food · 2025Review
- Association between composite dietary antioxidant index and epilepsy in American population: a cross-sectional study from NHANES.BMC public health · 2024Article
- Epidemiology and morbidity of spina bifida in Hispanic Americans: a systematic review.BMJ public health · 2024Article
- Multivitamin Use Among Hispanic Women of Reproductive Age in the United States, 2013-2022.Journal of women's health (2002) · 2024Article
- Update on the impact of voluntary folic acid fortification of corn masa flour on red blood cell folate concentrations-National Health and Nutrition Examination Survey, 2011-March 2020.Birth defects research · 2024Article
- Folate and vitamin B12 usual intake and biomarker status by intake source in United States adults aged ≥19 y: NHANES 2007-2018.The American journal of clinical nutrition · 2023Article
- The impact of voluntary folate fortification of corn masa flour on US pregnancies complicated by neural tube defects.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Joint effect of maternal pre-pregnancy body mass index and folic acid supplements on gestational diabetes mellitus risk: a prospective cohort study.BMC pregnancy and childbirth · 2023Article
- Focused Revision: Policy statement on folic acid and neural tube defects.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Impact of Voluntary Folic Acid Fortification of Corn Masa Flour on RBC Folate Concentrations in the U.S. (NHANES 2011-2018).Nutrients · 2021Article
- Engaging Community Members to Eradicate Health Disparities.American journal of public health · 2020Article
- Periconceptional folic acid supplementation and risk of parent-reported asthma in children at 4-6 years of age.ERJ open research · 2020Article
- Sociodemographic, health behavioral, and clinical risk factors for anotia/microtia in a population-based case-control study.International journal of pediatric otorhinolaryngology · 2019Article
- Article
- Hispanic Women's Perceptions of Neural Tube Defects and Folic Acid Supplementation: A Qualitative Study.Women's health issues : official publication of the Jacobs Institute of Women's HealthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Although strides have been made in preventing neural tube defects (NTDs), Hispanic women remain more likely to have a baby born with an NTD and less likely to know the benefits of, or consume, folic acid than women of other race/ethnic groups. In 1998, the U.S. Food and Drug Administration (FDA) mandated that all enriched cereal grain products be fortified with folic acid; however, corn masa flour (CMF), used to make many corn products that are a diet staple of many Hispanic groups, was not included under this regulation. In 2006, a Working Group began a collaboration to address this disparity by pursuing a petition to FDA to allow folic acid to be added voluntarily to CMF. The petition process was a monumental effort that required collaboration and commitment by partners representing the affected population, manufacturers, scientists, and others. The petition was approved in 2016 and folic acid is now added to CMF products, with expected results of more women achieving the recommended daily folic acid intake, more infants born per year without an NTD, and millions of dollars in direct medical expenditures averted. This 10-year public-private partnership brought together diverse groups that traditionally have different goals. The Working Group continues to work toward ensuring that fortified CMF products are available to the consumer, with the end goal of achieving a reduction in NTD-affected pregnancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.