ArticleJournal of biomedical optics2017
X-ray luminescence computed tomography using a focused x-ray beam.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Spatial Resolution for X-ray Excited Luminescence Chemical Imaging (XELCI).Chemical & biomedical imaging · 2024Article
- Oxygenation imaging in deep tissue with X-Ray luminescence computed tomography (XLCT).Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Superfast Scan of Focused X-Ray Luminescence Computed Tomography Imaging.IEEE access : practical innovations, open solutions · 2023Article
- Contrast agents for x-ray luminescence computed tomography.Applied optics · 2021Article
- Focused x-ray luminescence imaging system for small animals based on a rotary gantry.Journal of biomedical optics · 2021Article
- Radiation dose estimation for pencil beam X-ray luminescence computed tomography imaging.Journal of X-ray science and technology · 2021Article
- X-ray luminescence imaging for small animals.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- High-resolution x-ray luminescence computed tomography.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Method for improving the spatial resolution of narrow x-ray beam-based x-ray luminescence computed tomography imaging.Journal of biomedical optics · 2019Article
- Focused x-ray luminescence computed tomography: experimental studies.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Background luminescence in x-ray luminescence computed tomography (XLCT) imaging.Applied optics · 2019Article
- Time domain X-ray luminescence computed tomography: numerical simulations.Biomedical optics express · 2019Article
- Optical and x-ray technology synergies enabling diagnostic and therapeutic applications in medicine.Journal of biomedical optics · 2018Review
- Gamma rays excited radioluminescence tomographic imaging.Biomedical engineering online · 2018Article
- A microbeam grazing-incidence approach to L-shell x-ray fluorescence measurements of lead concentration in bone and soft tissue phantoms.Physiological measurement · 2018Article
- Super-Fast Three-Dimensional Focused X-ray Luminescence Computed Tomography with a Gated Photon Counter.Proceedings of SPIE--the International Society for Optical EngineeringArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Due to the low x-ray photon utilization efficiency and low measurement sensitivity of the electron multiplying charge coupled device camera setup, the collimator-based narrow beam x-ray luminescence computed tomography (XLCT) usually requires a long measurement time. We, for the first time, report a focused x-ray beam-based XLCT imaging system with measurements by a single optical fiber bundle and a photomultiplier tube (PMT). An x-ray tube with a polycapillary lens was used to generate a focused x-ray beam whose x-ray photon density is 1200 times larger than a collimated x-ray beam. An optical fiber bundle was employed to collect and deliver the emitted photons on the phantom surface to the PMT. The total measurement time was reduced to 12.5 min. For numerical simulations of both single and six fiber bundle cases, we were able to reconstruct six targets successfully. For the phantom experiment, two targets with an edge-to-edge distance of 0.4 mm and a center-to-center distance of 0.8 mm were successfully reconstructed by the measurement setup with a single fiber bundle and a PMT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.