ReviewIndian journal of pediatrics2018
Asthma, GERD and Obesity: Triangle of Inflammation.
Review in Indian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Gastroesophageal Reflux Burden Before and After Exercise Challenge in Children with Poorly Controlled Asthma: A 48-Hour MII-pH Study.Advances in respiratory medicine · 2026Article
- ALK5 inhibition reduces HDM-induced inflammation and oxidative injury by regulating KLF4-mediated glycolysis in BEAS-2B cells.Journal of bioenergetics and biomembranes · 2026Article
- Gene-Diet interaction between FTO rs9939609 and fiber intake in relation to GERD susceptibility.Molecular biology reports · 2025Article
- Article
- Co-Occurrence of Psoriasis and Asthma in the Pediatric Population: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Exploring the Link between Oxidative Stress, Selenium Levels, and Obesity in Youth.International journal of molecular sciences · 2024Review
- ORMDL3‑mediated bronchial epithelial pyroptosis leads to lung inflammation in obese mice with asthma.Molecular medicine reports · 2023Article
- The association between erosive toothwear and asthma - is it significant? A meta-analysis.BDJ open · 2023Article
- Article
- Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Review
- Neutrophils and Asthma.Diagnostics (Basel, Switzerland) · 2022Review
- Current unmet needs and potential solutions to uncontrolled asthma.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Do not forget asthma comorbidities in pediatric severe asthma!Frontiers in pediatrics · 2022Review
- Energy-drink consumption is associated with asthma, allergic rhinitis, and atopic dermatitis in Korean adolescents.European journal of clinical nutrition · 2021Article
- Bidirectional association between GERD and asthma in children: two longitudinal follow-up studies using a national sample cohort.Pediatric research · 2020Article
- Role of Obesity in Otorhinolaryngologic Diseases.Current allergy and asthma reports · 2019Review
- Asthma medication usage is significantly reduced following bariatric surgery.Surgical endoscopy · 2019Article
- Advances in Asthma - III.Indian journal of pediatrics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is increasing prevalence of both asthma and obesity in children globally in recent years. Various epidemiological studies link obesity as a risk factor for asthma and suggest a possible causal association. Obesity asthma phenotype is considered as distinct in view of greater severity and poor asthma control. Various mechanisms underlying this phenotype have been suggested including mechanical effects of obesity and systemic inflammation, but still the exact mechanism is unclear. Also, the comorbidities like gastroesophageal reflux disease (GERD) and sleep disordered breathing (SDB) lead to inflammation in airways and contribute to asthma obesity association. A better understanding of mechanisms by which obesity and GERD lead to inflammation in airways and increase the risk of asthma may provide insight towards targeted treatment approach of these patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.