Evidence map›Paper›PMID 29127493›Full record

ReviewPflugers Archiv : European journal of physiology2018

Late sodium current associated cardiac electrophysiological and mechanical dysfunction.

Shandong Yu, Gang Li, Christopher L-H Huang, Ming Lei, Lin Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Safety and Short-Term Effects of Empagliflozin in Patients with Heart Failure and End-Stage Renal Disease.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Trial
  2. Review
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  12. Late sodium current in synergism with CaPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  13. Conductance Changes of NaPharmaceuticals (Basel, Switzerland) · 2023
    Article
  14. Article
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  18. An Overview of the Cardiorenal Protective Mechanisms of SGLT2 Inhibitors.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Shandong YuDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Gang LiDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Christopher L-H HuangPhysiological laboratory, University of Cambridge, Cambridge, UK.
Ming LeiDepartment of Pharmacology, University of Oxford, Oxford, UK. ming.lei@pharm.ox.ac.uk.
Lin WuDepartment of Cardiology, Peking University First Hospital, Beijing, China. lin_wu@163.com.
Peking University First Hospital · CNMinistry of Education of the People's Republic of China · CNPhysiological Society · GBUniversity of Oxford · GB

Funding

British Heart Foundation PG/11/59/29006British Heart Foundation PG/14/80/31106British Heart Foundation PG/16/67/32340Chinese National Natural Science Foundation 81170156Chinese National Natural Sciences Foundation 81270253Chinese National Natural Sciences Foundation 81430098Chinese National Natural Sciences Foundation 81470454Medical Research Council G1002647
6 · The paper itself

Abstract

Late sodium current (I

Indexed as

Action PotentialsAnimalsAnti-Arrhythmia AgentsArrhythmias, CardiacHumansMyocytes, CardiacSodium Channel BlockersSodium ChannelsAnti-Arrhythmia AgentsSodium Channel BlockersSodium ChannelsCardiac arrhythmiasINaLLate sodium currentMechanical dysfunction antiarrhythmic drugs

Identifiers

PMID29127493
OpenAlexW2767771685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.